BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
6/9/2026 9:23:52 AM | Browse: 0 | Download: 0
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 118531
Country China
Received
2026-01-05 03:22
Peer-Review Started
2026-01-05 03:23
First Decision by Editorial Office Director
2026-01-26 09:11
Return for Revision
2026-01-26 09:46
Revised
2026-02-07 16:35
Publication Fee Transferred
Second Decision by Editor
2026-03-19 02:33
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-03-19 08:24
Articles in Press
2026-03-19 08:24
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-05-26 08:24
Publish the Manuscript Online
2026-06-09 09:23
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Is salvage surgery necessary for non-R0 endoscopic resection of small rectal neuroendocrine tumors?
Manuscript Source Invited Manuscript
All Author List Shi-Yong Lin, Ze-Hua Li, Guo-Liang Xu, Jun Weng and Kun-Hao Bai
ORCID
Author(s) ORCID Number
Shi-Yong Lin http://orcid.org/0000-0002-3881-6422
Ze-Hua Li http://orcid.org/0000-0001-5624-0087
Guo-Liang Xu http://orcid.org/0000-0002-8882-2636
Jun Weng http://orcid.org/0000-0003-0792-1526
Kun-Hao Bai http://orcid.org/0000-0003-1184-7576
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 82403973, 82373118
Guangdong Basic and Applied Basic Research Foundation 2023A1515010828
Corresponding Author Kun-Hao Bai, Associate Chief Physician, MD, PhD, Department of Endoscopy, Sun Yat-sen University Cancer Center, No. 651 Dongfengdong Street, Yuexiu District, Guangzhou 510060, Guangdong Province, China. baikh@sysucc.org.cn
Key Words Rectal neuroendocrine tumors; Endoscopic resection; Non-R0 resection; Salvage surgery; Follow-up
Core Tip Rectal neuroendocrine tumors (r-NETs) are diminutive but potentially malignant neoplasms. The rate of R0 resection for endoscopic resection of small r-NETs is nearly 90%. However, there is still controversy about subsequent treatment options for patients with non-R0 endoscopically resected r-NETs. This retrospective study investigated 38 patients with non-R0 endoscopically resected r-NETs. Of these, 30 underwent salvage surgery while 8 received follow-up only. Postoperative pathology following salvage surgery indicated an absence of tumor cells in all 30 patients. No evidence of local tumor recurrence or distant metastasis was observed in all 38 patients during an average follow-up duration of 46.4 ± 14.8 months. These findings suggest that salvage surgery may not be essential for patients with non-R0 endoscopically resected r-NETs, with regular follow-up being a safe alternative.
Publish Date 2026-06-09 09:23
Citation

Lin SY, Li ZH, Xu GL, Weng J, Bai KH. Is salvage surgery necessary for non-R0 endoscopic resection of small rectal neuroendocrine tumors? World J Gastrointest Oncol 2026; 18(6): 118531

URL https://www.wjgnet.com/1948-5204/full/v18/i6/118531.htm
DOI https://doi.org/10.4251/wjgo.v18.i6.118531
Full Article (PDF) WJGO-18-118531-with-cover.pdf
Manuscript File 118531_Auto_Edited_103552.docx
Answering Reviewers 118531-answering-reviewers.pdf
Audio Core Tip 118531-audio.wav
Biostatistics Review Certificate 118531-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 118531-conflict-of-interest-statement.pdf
Copyright License Agreement 118531-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 118531-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 118531-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 118531-non-native-speakers.pdf
Peer-review Report 118531-peer-reviews.pdf
Scientific Misconduct Check 118531-scientific-misconduct-check.png
Scientific Editor Work List 118531-scientific-editor-work-list.pdf
CrossCheck Report 118531-crosscheck-report.pdf