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Articles Published Processes
6/26/2026 9:50:18 AM | Browse: 0 | Download: 0
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Received |
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2026-01-05 08:31 |
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Peer-Review Started |
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2026-01-05 08:33 |
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First Decision by Editorial Office Director |
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2026-01-28 09:10 |
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Return for Revision |
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2026-01-28 09:10 |
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Revised |
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2026-02-10 02:48 |
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Publication Fee Transferred |
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2026-02-15 14:23 |
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Second Decision by Editor |
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2026-04-03 02:42 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-04-03 08:10 |
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Articles in Press |
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2026-04-03 08:10 |
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Edit the Manuscript by Language Editor |
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2026-04-06 20:55 |
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Typeset the Manuscript |
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2026-06-16 01:02 |
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Publish the Manuscript Online |
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2026-06-26 09:50 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© Author(s) (or their employer(s)) 2026. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Bile acid receptor signaling in metabolic dysfunction-associated steatotic liver disease: Mechanistic insights and emerging therapeutic strategies
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Sanjay Bandyopadhyay, Shambo Samrat Samajdar, Shatavisa Mukherjee and Shashank R Joshi |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Sanjay Bandyopadhyay, DM, FRCP, Head, Department of Gastroenterology, ILS Dumdum Hospital, 1 Mall Road, Kolkata 700080, West Bengal, India. drsanjaygastro@gmail.com |
| Key Words |
Metabolic dysfunction-associated steatotic liver disease; Bile acid receptors; Farnesoid X receptor; Takeda G-protein-coupled receptor 5; Norursodeoxycholic acid |
| Core Tip |
Metabolic dysfunction-associated steatotic liver disease (MASLD) represents a global health challenge with limited pharmacological options. This review highlights the emerging role of bile acid receptors - particularly farnesoid X receptor (FXR) and Takeda G-protein-coupled receptor 5 - as therapeutic targets in MASLD. It synthesizes recent advances in receptor signaling, gut microbiota-bile acid interactions, and the development of FXR agonists, norursodeoxycholic acid, and dual FXR/Takeda G-protein-coupled receptor 5 agents. The review also outlines future directions in precision hepatology, proposing receptor-specific, microbiome-informed strategies for managing MASLD. |
| Publish Date |
2026-06-26 09:50 |
| Citation |
Bandyopadhyay S, Samajdar SS, Mukherjee S, Joshi SR. Bile acid receptor signaling in metabolic dysfunction-associated steatotic liver disease: Mechanistic insights and emerging therapeutic strategies. World J Hepatol 2026; 18(6): 118548
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| URL |
https://www.wjgnet.com/1948-5182/full/v18/i6/118548.htm |
| DOI |
https://doi.org/10.4254/wjh.118548 |
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