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6/15/2026 8:38:29 AM | Browse: 1 | Download: 0
Publication Name World Journal of Nephrology
Manuscript ID 118565
Country Thailand
Received
2026-01-06 06:35
Peer-Review Started
2026-01-06 06:37
First Decision by Editorial Office Director
2026-01-16 06:58
Return for Revision
2026-01-16 06:58
Revised
2026-01-27 15:16
Publication Fee Transferred
Second Decision by Editor
2026-02-24 02:44
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-24 07:07
Articles in Press
2026-02-24 07:07
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-05-26 09:23
Publish the Manuscript Online
2026-06-15 08:38
ISSN 2220-6124 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Urology & Nephrology
Manuscript Type Minireviews
Article Title Microparticles at the crossroads of the gut-kidney axis: Mechanistic drivers and therapeutic horizons in hemodialysis
Manuscript Source Invited Manuscript
All Author List Thansita Bhunyakarnjanarat, Asada Leelahavanichkul and Wiwat Chancharoenthana
ORCID
Author(s) ORCID Number
Asada Leelahavanichkul http://orcid.org/0000-0002-5566-6403
Wiwat Chancharoenthana http://orcid.org/0000-0002-2965-146X
Funding Agency and Grant Number
Funding Agency Grant Number
Mahidol University (MU’s Strategic Research Fund): Fiscal Year 2023 MU-SRF-PF-03A/66
Corresponding Author Wiwat Chancharoenthana, MD, PhD, Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, 16/F Ratchanakarin Building 420/6 Rajvithi Road, Ratchathewi, Bangkok 10400, Thailand. wiwat.cha@mahidol.ac.th
Key Words Microparticles; Gut-kidney axis; Hemodialysis; Uremic toxins; Chronic kidney disease
Core Tip Microparticles (MPs) are increasingly recognized as pivotal mediators in the gut-kidney axis, particularly in hemodialysis patients. This review elucidates how gut dysbiosis triggers the release of host and microbial MPs, which transport uremic toxins and pro-inflammatory cargo to drive endothelial dysfunction and cardiovascular complications. By synthesizing current evidence on MP biogenesis and their role as biomarkers, we highlight novel therapeutic horizons, including microbiota modulation and MP-targeted interventions, aimed at disrupting this pathogenic dialogue to improve clinical outcomes in end-stage kidney disease.
Publish Date 2026-06-15 08:38
Citation

Bhunyakarnjanarat T, Leelahavanichkul A, Chancharoenthana W. Microparticles at the crossroads of the gut-kidney axis: Mechanistic drivers and therapeutic horizons in hemodialysis. World J Nephrol 2026; 15(2): 118565

URL https://www.wjgnet.com/2220-6124/full/v15/i2/118565.htm
DOI https://doi.org/10.5527/wjn.v15.i2.118565
Full Article (PDF) WJN-15-118565-with-cover.pdf
Manuscript File 118565_Auto_Edited-WJJ.docx
Answering Reviewers 118565-answering-reviewers.pdf
Audio Core Tip 118565-audio.mp3
Conflict-of-Interest Disclosure Form 118565-conflict-of-interest-statement.pdf
Copyright License Agreement 118565-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 118565-non-native-speakers.pdf
Peer-review Report 118565-peer-reviews.pdf
Scientific Misconduct Check 118565-scientific-misconduct-check.png
Scientific Editor Work List 118565-scientific-editor-work-list.pdf
CrossCheck Report 118565-crosscheck-report.pdf