| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Calcium-dependent signaling protein family member S100A11 promotes liver and adipose lipid accumulation through fibroblast growth factor 21
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Qian-Qian Zhang, Xiao-Qing Lu, Bing-Zhen Shang, Ling-Chao Liu, En-Ting Lu, Hua-Yang Li, Ming-Ming Xia, Yu-Xin Jin, Wei-Zhen Zhang, Yi Zhang, Jing-Yan Han and Yin Li |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Key Research and Development Program of China |
No. 2020YFA0803801 |
| National Natural Science Foundation of China |
No. 81873568 |
| Key Research and Liao Ning Revitalization Talents Program |
No. XLYC2412037 |
|
| Corresponding Author |
Yin Li, Associate Professor, MD, PhD, Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, No. 38 Xueyuan Road, Haidian District, Beijing 100191, China. yinli@bjmu.edu.cn |
| Key Words |
Non-alcoholic fatty liver disease; S100A11; Fibroblast growth factor 21; Type 2 diabetes mellitus; Obesity |
| Core Tip |
This study reveals that the calcium-binding protein S100A11 promotes hepatic and adipose lipid accumulation by upregulating fibroblast growth factor 21, identifying S100A11 as a novel potential therapeutic target for obesity-related metabolic disorders. |
| Publish Date |
2026-06-30 13:35 |
| Citation |
Zhang QQ, Lu XQ, Shang BZ, Liu LC, Lu ET, Li HY, Xia MM, Jin YX, Zhang WZ, Zhang Y, Han JY, Li Y. Calcium-dependent signaling protein family member S100A11 promotes liver and adipose lipid accumulation through fibroblast growth factor 21. World J Gastroenterol 2026; 32(25): 118597
|
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i25/118597.htm |
| DOI |
https://doi.org/10.3748/wjg.118597 |
