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Articles Published Processes
4/21/2026 9:00:10 AM | Browse: 4 | Download: 19
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Received |
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2026-01-07 06:43 |
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Peer-Review Started |
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2026-01-07 06:46 |
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First Decision by Editorial Office Director |
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2026-01-14 08:14 |
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Return for Revision |
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2026-01-14 08:14 |
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Revised |
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2026-01-27 10:11 |
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Publication Fee Transferred |
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2026-01-29 09:12 |
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Second Decision by Editor |
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2026-02-24 02:40 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-02-24 04:11 |
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Articles in Press |
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2026-02-24 04:11 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-04-02 08:04 |
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Publish the Manuscript Online |
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2026-04-21 09:00 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Immunology |
| Manuscript Type |
Review |
| Article Title |
Host and gut microbiota crosstalk: A new paradigm for colorectal cancer immunotherapy
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Dong-Dong Ti, Peng Liu, Chun-Yan Wu, Zhi-Ming Shi, Shu-Ming Guo and Zhan-Cheng Gao |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
31971378 |
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| Corresponding Author |
Shu-Ming Guo, Clinical Medicine Research Center, Linfen Central Hospital, No. 17 Jiefang West Road, Yaodu District, Linfen 041000, Shanxi Province, China. guoshuming70@163.com |
| Key Words |
Colorectal cancer; Gut microbiota; Immunotherapy; Immune cell; Tumor microenvironment |
| Core Tip |
From birth onward, host health is closely linked to the delicate balance of ecological microbiota composition. The microbiota utilizes distinct enzymatic capabilities to metabolize nutrients and produce immunomodulatory byproducts that influence organ function and behavior. A strong and rapid association has been identified between gut microbiome dysbiosis, defined as a disruption in microbial load or diversity, colorectal cancer pathogenesis, and responsiveness to immunotherapy. Therefore, clarify the mechanism of gut microbiome dysbiosis and develop microbe-based intervention through health-oriented and adaptable mechanisms, such as oral probiotic administration, will become an indispensable component of colorectal cancer immunotherapy in the future. |
| Publish Date |
2026-04-21 09:00 |
| Citation |
Ti DD, Liu P, Wu CY, Shi ZM, Guo SM, Gao ZC. Host and gut microbiota crosstalk: A new paradigm for colorectal cancer immunotherapy. World J Clin Oncol 2026; 17(4): 118606 |
| URL |
https://www.wjgnet.com/2218-4333/full/v17/i4/118606.htm |
| DOI |
https://dx.doi.org/10.5306/wjco.v17.i4.118606 |
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