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Articles Published Processes
2/11/2015 5:56:00 PM | Browse: 1189 | Download: 1571
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Received |
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2014-06-09 08:00 |
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Peer-Review Started |
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2014-06-10 10:18 |
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To Make the First Decision |
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2014-08-06 17:15 |
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Return for Revision |
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2014-08-14 09:43 |
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Revised |
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2014-08-24 21:07 |
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Second Decision |
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2014-10-15 12:36 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-10-15 17:44 |
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Articles in Press |
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2014-10-15 17:57 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-01-22 08:38 |
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Publish the Manuscript Online |
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2015-02-11 17:56 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Surgery |
Manuscript Type |
Autobiography |
Article Title |
Nitrite, a novel method to decrease ischemia/reperfusion injury in the rat liver
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Bergthor Björnsson, Linda Bojmar, Hans Olsson, Tommy Sundqvist and Per Sandström |
Funding Agency and Grant Number |
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Corresponding Author |
Bergthor Björnsson, MD, Department of Surgery, County Council of Östergötland, Garnisonsvägen, 581 85 Linköping, Sweden. bergthor.bjornsson@lio.se |
Key Words |
Ischemia-reperfusion injury; Nitrite; Liver ischemia; Liver surgery; Microdialysis; Nitric oxide; Inducible nitric oxide synthase |
Core Tip |
Nitric oxide has an important protective effect against liver ischemia/reperfusion injury (IRI), although large levels of the substance may increase IRI. The total levels of nitrite and nitrate decrease in the liver tissue during ischemia. Because nitrite can be reduced to nitric oxide (NO) in an acidic environment, this de?crease may be due to NO formation. In this study, the administration of nitrite before liver ischemia/re?perfusion reduced the IRI per evaluation with transa?minases, liver microdialysis and histology. |
Publish Date |
2015-02-11 17:56 |
Citation |
Björnsson B, Bojmar L, Olsson H, Sundqvist T, Sandström P. Nitrite, a novel method to decrease ischemia/reperfusion injury in the rat liver. World J Gastroenterol 2015; 21(6): 1775-1783 |
URL |
http://www.wjgnet.com/1007-9327/full/v21/i6/1775.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v21.i6.1775 |
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