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Articles Published Processes
8/11/2026 6:12:02 AM | Browse: 5 | Download: 1
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Received |
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2026-01-08 06:44 |
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Peer-Review Started |
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2026-01-08 06:46 |
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First Decision by Editorial Office Director |
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2026-01-19 09:00 |
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Return for Revision |
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2026-01-19 09:00 |
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Revised |
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2026-01-21 13:10 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-03-05 02:53 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-03-05 09:32 |
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Articles in Press |
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2026-03-05 09:32 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-07-31 10:37 |
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Publish the Manuscript Online |
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2026-08-11 06:12 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Opinion Review |
| Article Title |
Stage-aware programmed death ligand 1 assessment in gastric cancer: Implications for perioperative immunotherapy
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Hou-Shu Tu, Meng-Lin Chen, Jing Hong, Sai Li and Ling He |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ling He, PhD, Professor, Department of Gastroenterology, Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, No. 445 Bayi Avenue, Nanchang 330006, Jiangxi Province, China. heling118@126.com |
| Key Words |
Biomarkers; Immunotherapy; Neoplasm staging; Precision medicine; Prognosis; Programmed death-ligand 1; Stomach neoplasms; Tumor microenvironment |
| Core Tip |
This Opinion Review emphasizes the stage- and context-dependent interpretation of PD-L1 in gastric cancer (GC). We summarize current advances in PD-L1 assessment—including combined positive score, spatial profiling, and multi-omics integration—and discuss how tumor stage, immune microenvironment, and T-cell functionality influence its prognostic and predictive value. The review provides a framework for integrating PD-L1 into perioperative immunotherapy, highlighting adaptive, biomarker-guided strategies to optimize patient selection and therapeutic outcomes. By bridging molecular insights with personalized treatment, this work offers practical guidance for both clinicians and researchers in precision GC management. |
| Publish Date |
2026-08-11 06:12 |
| Citation |
Tu HS, Chen ML, Hong J, Li S, He L. Stage-aware programmed death ligand 1 assessment in gastric cancer: Implications for perioperative immunotherapy. World J Gastroenterol 2026; 32(33): 118672
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| URL |
https://www.wjgnet.com/1007-9327/full/v32/i33/118672.htm |
| DOI |
https://doi.org/10.3748/wjg.118672 |
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