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6/8/2026 9:12:21 AM | Browse: 3 | Download: 1
Publication Name World Journal of Gastroenterology
Manuscript ID 118782
Country China
Received
2026-01-12 06:50
Peer-Review Started
2026-01-12 06:52
First Decision by Editorial Office Director
2026-01-19 09:04
Return for Revision
2026-01-19 09:04
Revised
2026-01-31 12:46
Publication Fee Transferred
2026-02-03 09:45
Second Decision by Editor
2026-03-16 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-03-16 11:48
Articles in Press
2026-03-16 11:48
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-05-29 07:37
Publish the Manuscript Online
2026-06-08 09:12
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright Given that Immunoglobulin-related digestive system disorders frequently mimic malignancies, leading to misdiagnosis, this review systematically maps the clinical spectrum from classical (pancreato-biliary) to rare (esophageal/mesenteric) manifestations. A key highlight is the paradigm shift from single-marker diagnosis to multidimensional biomarker assessment (e.g., plasma blasts, interferon-α-interleukin-33 axis). It focuses on the utility of these novel markers in monitoring disease activity and predicting fibrosis, providing evidence-based strategies for early recognition and personalized management.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Minireviews
Article Title Clinical features and biomarker research advances in immunoglobulin 4-related digestive system disorders
Manuscript Source Unsolicited Manuscript
All Author List Yue Pan and Yu-Zhang Jiang
ORCID
Author(s) ORCID Number
Yu-Zhang Jiang http://orcid.org/0000-0002-8544-9485
Funding Agency and Grant Number
Funding Agency Grant Number
Open Research Project of the Huai'an ‘Tian Yixing’ Key Laboratory of Medical Laboratory Science HAP202004
Corresponding Author Yu-Zhang Jiang, Professor, Department of Laboratory Medicine, The Affiliated Huai'an No. 1 People's Hospital of Nanjing Medical University, No. 1 West Huanghe Road, Huai’an 223300, Jiangsu Province, China. jyz8848@163.com
Key Words Immunoglobulin 4-related disease; Biomarkers; Digestive system; Diagnosis; Pathogenesis
Core Tip Given that Immunoglobulin-related digestive system disorders frequently mimic malignancies, leading to misdiagnosis, this review systematically maps the clinical spectrum from classical (pancreato-biliary) to rare (esophageal/mesenteric) manifestations. A key highlight is the paradigm shift from single-marker diagnosis to multidimensional biomarker assessment (e.g., plasma blasts, interferon-α-interleukin-33 axis). It focuses on the utility of these novel markers in monitoring disease activity and predicting fibrosis, providing evidence-based strategies for early recognition and personalized management.
Publish Date 2026-06-08 09:12
Citation

Pan Y, Jiang YZ. Clinical features and biomarker research advances in immunoglobulin 4-related digestive system disorders. World J Gastroenterol 2026; 32(23): 118782

URL https://www.wjgnet.com/1007-9327/full/v32/i23/118782.htm
DOI https://doi.org/10.3748/wjg.v32.i23.118782
Full Article (PDF) WJG-32-118782-with-cover.pdf
Manuscript File 118782_Auto_Edited-WJJ.docx
Answering Reviewers 118782-answering-reviewers.pdf
Audio Core Tip 118782-audio.mp3
Conflict-of-Interest Disclosure Form 118782-conflict-of-interest-statement.pdf
Copyright License Agreement 118782-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 118782-non-native-speakers.pdf
Peer-review Report 118782-peer-reviews.pdf
Scientific Misconduct Check 118782-scientific-misconduct-check.png
Scientific Editor Work List 118782-scientific-editor-work-list.pdf
CrossCheck Report 118782-crosscheck-report.pdf