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8/3/2026 1:23:54 AM | Browse: 2 | Download: 0
Publication Name World Journal of Clinical Pediatrics
Manuscript ID 118791
Country Italy
Received
2026-01-12 07:07
Peer-Review Started
2026-01-12 07:08
First Decision by Editorial Office Director
2026-02-13 07:36
Return for Revision
2026-02-13 07:36
Revised
2026-02-17 16:28
Publication Fee Transferred
2026-05-06 12:52
Second Decision by Editor
2026-05-29 03:06
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-05-29 10:32
Articles in Press
2026-05-29 10:32
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-07-23 03:37
Publish the Manuscript Online
2026-08-03 01:23
ISSN 2219-2808 (online)
Open Access Open-Access: This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Meta-Analysis
Article Title Lactobacillus supplementation for Helicobacter pylori eradication in children: A language-inclusive systematic review and meta-analysis of efficacy and safety
Manuscript Source Unsolicited Manuscript
All Author List Vanessa Nadia Dargenio, Sara Ricciardi, Martina Begucci, Giovanni La grasta, Nadia Maggi, Costantino Dargenio, Stefania Paola Castellaneta, Fernanda Cristofori and Ruggiero Francavilla
ORCID
Author(s) ORCID Number
Fernanda Cristofori http://orcid.org/0000-0001-5849-8110
Ruggiero Francavilla http://orcid.org/0000-0002-4603-974X
Funding Agency and Grant Number
Corresponding Author Fernanda Cristofori, MD, PhD, Department of Biomedical Science and Human Oncology, University of Bari, 1 Piazza Umberto I, Bari 70121, Puglia, Italy. fernandacristofori@gmail.com
Key Words Probiotic; Lactobacillus; Helicobacter; Infection; Gastritis; Children
Core Tip Adjunctive Lactobacillus supplementation significantly enhances Helicobacter pylori (H. pylori) eradication rates in children and reduces treatment-related adverse effects. Evidence from this meta-analysis, which includes a substantial number of non-English and Chinese studies, demonstrates that probiotics are particularly effective when combined with standard triple therapy and when administered at higher doses. These findings support Lactobacillus probiotics as a safe, effective, and globally relevant complementary strategy for optimizing pediatric H. pylori treatment.
Publish Date 2026-08-03 01:23
Citation

Dargenio VN, Ricciardi S, Begucci M, La grasta G, Maggi N, Dargenio C, Castellaneta SP, Cristofori F, Francavilla R. Lactobacillus supplementation for Helicobacter pylori eradication in children: A language-inclusive systematic review and meta-analysis of efficacy and safety. World J Clin Pediatr 2026; 15(3): 118791

URL https://www.wjgnet.com/2219-2808/full/v15/i3/118791.htm
DOI https://doi.org/10.5409/wjcp.118791
Full Article (PDF) WJCP-15-118791-with-cover.pdf
PRISMA 2009 Checklist 118791-PRISMA-2009-Checklist.pdf
Manuscript File 118791_Auto_Edited_005633.docx
Answering Reviewers 118791-answering-reviewers.pdf
Audio Core Tip 118791-audio.m4a
Biostatistics Review Certificate 118791-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 118791-conflict-of-interest-statement.pdf
Copyright License Agreement 118791-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 118791-non-native-speakers.pdf
Supplementary Material 118791-supplementary-material.pdf
Peer-review Report 118791-peer-reviews.pdf
Scientific Misconduct Check 118791-scientific-misconduct-check.png
Scientific Editor Work List 118791-scientific-editor-work-list.pdf
CrossCheck Report 118791-crosscheck-report.pdf