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Articles Published Processes
8/21/2026 3:32:18 AM | Browse: 6 | Download: 4
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Received |
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2026-01-20 01:31 |
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Peer-Review Started |
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2026-01-20 01:32 |
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First Decision by Editorial Office Director |
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2026-02-06 10:45 |
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Return for Revision |
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2026-02-06 10:45 |
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Revised |
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2026-02-16 01:28 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-06-09 02:35 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-06-09 07:25 |
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Articles in Press |
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2026-06-09 07:25 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-07-31 10:46 |
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Publish the Manuscript Online |
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2026-08-21 03:32 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Microbiology |
| Manuscript Type |
Opinion Review |
| Article Title |
Polyethylene glycol-based bowel preparation and gut dysbiosis: Clinical implications beyond colon cleansing
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ana Clara Correia Melgaço, Adriano Francisco Alves and Wallace Felipe Blohem Pessoa |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Wallace Felipe Blohem Pessoa, Adjunct Professor, PhD, Department of Biomedical Sciences, Federal University of Paraíba, Via Pau Brasil, S/N, João Pessoa, Paraíba, 58050-585, Brazil, João Pessoa 58050-585, Paraíba, Brazil. wall.bmd@gmail.com |
| Key Words |
Polyethylene glycol; Dysbiosis; Bowel preparation; Microbiota; Mucosal recovery; Infection risk |
| Core Tip |
Polyethylene glycol (PEG)-based bowel preparation may transiently alter gut microbial diversity, mucus barrier integrity, and short-chain fatty acid production. Although these ecological changes are increasingly associated with immune modulation and postoperative outcomes, current evidence remains heterogeneous and largely observational. Suitably, this opinion review critically examines the mechanisms and potential clinical implications of PEG-induced dysbiosis. The review also emphasizes the need for microbiota-preserving bowel preparation strategies and personalized approaches based on host resilience and baseline microbiota composition. |
| Publish Date |
2026-08-21 03:32 |
| Citation |
Melgaço ACC, Alves AF, Pessoa WFB. Polyethylene glycol-based bowel preparation and gut dysbiosis: Clinical implications beyond colon cleansing. World J Gastroenterol 2026; 32(35): 118836
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| URL |
https://www.wjgnet.com/1007-9327/full/v32/i35/118836.htm |
| DOI |
https://doi.org/10.3748/wjg.118836 |
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