BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
5/14/2026 9:17:11 AM | Browse: 6 | Download: 25
 |
Received |
|
2026-01-27 09:51 |
|
Peer-Review Started |
|
2026-01-27 09:52 |
|
First Decision by Editorial Office Director |
|
2026-02-10 09:01 |
|
Return for Revision |
|
2026-02-10 09:01 |
|
Revised |
|
2026-02-26 21:50 |
 |
Publication Fee Transferred |
|
|
|
Second Decision by Editor |
|
2026-03-23 02:49 |
|
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2026-03-23 08:21 |
|
Articles in Press |
|
2026-03-23 08:21 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2026-04-20 06:21 |
|
Publish the Manuscript Online |
|
2026-05-14 09:17 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Basic Study |
| Article Title |
FNDC5 enhances quercetin-induced anoikis in pancreatic adenocarcinoma cells via focal adhesion kinase-dependent mechanisms
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hui-Feng Gao, Ke Zhang, Chien-Shan Cheng, Ye-Hua Shen and Hao Chen |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
No. 82074204 |
|
| Corresponding Author |
Hao Chen, Chief Physician, Department of Integrative Oncology, Fudan University Shanghai Cancer Center, No. 270 Dong’an Road, Shanghai 200032, China. chengkll@sina.com |
| Key Words |
FNDC5; Irisin; Quercetin; Pancreatic ductal adenocarcinoma; Anoikis; Focal adhesion kinase; Mitochondrial apoptosis; Chemosensitivity |
| Core Tip |
This study highlights that FNDC5 enhances quercetin-mediated growth inhibition, apoptosis, and anoikis through focal adhesion kinase/phosphatidylinositol 3-kinase/protein kinase B inhibition and mitochondrial apoptosis initiation. Our results provide further insight into the effect of irisin on pancreatic ductal adenocarcinoma (PAAD) cells and suggest a new strategy for PAAD treatment that combines quercetin and irisin. |
| Publish Date |
2026-05-14 09:17 |
| Citation |
Gao HF, Zhang K, Cheng CS, Shen YH, Chen H. FNDC5 enhances quercetin-induced anoikis in pancreatic adenocarcinoma cells via focal adhesion kinase-dependent mechanisms. World J Gastrointest Oncol 2026; 18(5): 118849 |
| URL |
https://www.wjgnet.com/1948-5204/full/v18/i5/118849.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v18.i5.118849 |
All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.
