| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Prospective Study |
| Article Title |
Diagnostic performance of fine-needle aspiration vs fine-needle biopsy in solid pancreatic lesions based on pathologist expertise: A prospective multicenter trial
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Antonio Afonso Miranda Neto, Vitor Ottoboni Brunaldi, Alberto Machado da Ponte Neto, Rafael Kemp, José Sebastião dos Santos, Joel Del Bel Pádua, Mariangela Ottoboni Brunaldi, Francisco Antonio Araújo Oliveira, José Ruver Lima Herculano Júnior, Danielle Azevedo Chacon, Guilherme Henrique Peixoto de Oliveira, Igor Braga Ribeiro, Sergio Eiji Matuguma and Eduardo Guimarães Hourneaux de Moura |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Igor Braga Ribeiro, Associate Research Scientist, MD, PhD, Department of Gastroenterology, University of São Paulo School of Medicine, Av. Dr Enéas de Carvalho Aguiar, 225, 6o andar, bloco 3, Cerqueira Cesar, São Paulo 05403-010, Brazil. igorbraga1@gmail.com |
| Key Words |
Pancreatic cancer; Endoscopic ultrasound; Fine-needle aspiration; Fine-needle biopsy |
| Core Tip |
The diagnostic yield of endoscopic ultrasound-guided tissue acquisition for solid pancreatic lesions is influenced by needle design, pathologist expertise, and institutional volume. This study shows that fine-needle biopsy provides superior diagnostic sensitivity compared with fine-needle aspiration when specimens are assessed by general pathologists, particularly in low-volume centers. These findings support fine-needle biopsy as a practical strategy to improve diagnostic reliability and reduce dependence on specialized cytopathology in routine clinical practice. |
| Publish Date |
2026-08-19 01:55 |
| Citation |
Miranda Neto AA, Brunaldi VO, da Ponte Neto AM, Kemp R, dos Santos JS, Pádua JDB, Brunaldi MO, Oliveira FAA, Herculano Júnior JRL, Chacon DA, de Oliveira GHP, Ribeiro IB, Matuguma SE, de Moura EGH. Diagnostic performance of fine-needle aspiration vs fine-needle biopsy in solid pancreatic lesions based on pathologist expertise: A prospective multicenter trial. World J Gastroenterol 2026; 32(34): 118873
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| URL |
https://www.wjgnet.com/1007-9327/full/v32/i34/118873.htm |
| DOI |
https://doi.org/10.3748/wjg.118873 |
