4/14/2026 5:58:20 AM | Browse: 0 | Download: 0
| Publication Name | World Journal of Cardiology |
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| Manuscript ID | 118879 |
| Country | United States |
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| ISSN | 1949-8462 (online) |
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| Open Access | This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright | ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247 |
| Permissions | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207 |
| Publisher | Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website | http://www.wjgnet.com |
| Category | Cardiac & Cardiovascular Systems | ||||||
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| Manuscript Type | Meta-Analysis | ||||||
| Article Title | Clinical outcomes of finerenone in heart failure: A systematic review and meta-analysis | ||||||
| Manuscript Source | Invited Manuscript | ||||||
| All Author List | Maneeth Mylavarapu, Madiha Kiyani, Andrew Ndakotsu, Vaibhav Vats, Nithin Karnan, Elizabeth Caroline Palaparthi, Mahnoor Anjum, Lakshmi Sai Meghana Kodali, Aneeza Jamshed and Fabio Enrique Parada Cabrera | ||||||
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| Corresponding Author | Maneeth Mylavarapu, MD, Senior Researcher, Department of Cardiology, Endeavor Health Cardiovascular Institute, 2100 Pfingsten Rd, Glenview, IL 60026, United States, Glenview, IL 60026, United States. dr.maneeth.mylavarapu@gmail.com | ||||||
| Key Words | Finerenone; Heart failure; Nonsteroidal mineralocorticoid receptor antagonists; Kansas City Cardiomyopathy Questionnaire; Hyperkalemia; Meta-analysis | ||||||
| Core Tip | Finerenone, a novel nonsteroidal mineralocorticoid receptor antagonist, has shown clear benefits in chronic kidney disease, but its specific impact on heart failure (HF) has required further synthesis. Our meta-analysis of 7457 patients reveals that finerenone significantly decreases the odds of worsening HF and enhances quality of life scores. However, potential safety signals, including hyperkalemia, suggest that while finerenone is a potent tool for managing HF, its use requires vigilant monitoring to balance clinical benefits against adverse events. | ||||||
| Publish Date | 2026-04-14 05:58 | ||||||
| Citation | Mylavarapu M, Kiyani M, Ndakotsu A, Vats V, Karnan N, Palaparthi EC, Anjum M, Kodali LSM, Jamshed A, Cabrera FEP. Clinical outcomes of finerenone in heart failure: A systematic review and meta-analysis. World J Cardiol 2026; 18(4): 118879 |
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| URL | https://www.wjgnet.com/1949-8462/full/v18/i4/118879.htm | ||||||
| DOI | https://dx.doi.org/10.4330/wjc.v18.i4.118879 |
| Full Article (PDF) | WJC-18-118879-with-cover.pdf |
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| PRISMA 2009 Checklist | 118879-PRISMA-2009-Checklist.pdf |
| Manuscript File | 118879_Auto_Edited_072503.docx |
| Answering Reviewers | 118879-answering-reviewers.pdf |
| Audio Core Tip | 118879-audio.m4a |
| Biostatistics Review Certificate | 118879-biostatistics-statement.pdf |
| Conflict-of-Interest Disclosure Form | 118879-conflict-of-interest-statement.pdf |
| Copyright License Agreement | 118879-copyright-assignment.pdf |
| Supplementary Material | 118879-supplementary-material.pdf |
| Peer-review Report | 118879-peer-reviews.pdf |
| Scientific Misconduct Check | 118879-scientific-misconduct-check.png |
| Scientific Editor Work List | 118879-scientific-editor-work-list.pdf |
| CrossCheck Report | 118879-crosscheck-report.pdf |