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8/11/2026 6:12:01 AM | Browse: 3 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 118981
Country China
Received
2026-01-16 06:00
Peer-Review Started
2026-01-16 06:01
First Decision by Editorial Office Director
2026-01-28 09:30
Return for Revision
2026-01-28 09:30
Revised
2026-02-03 14:15
Publication Fee Transferred
Second Decision by Editor
2026-03-04 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-03-04 09:39
Articles in Press
2026-03-04 09:39
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-07-31 06:46
Publish the Manuscript Online
2026-08-11 06:12
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © Author(s) (or their employer(s)) 2026. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Mathematical & Computational Biology
Manuscript Type Correspondence
Article Title Letter to the Editor: Integrative mechanistic exploration in gastrointestinal therapeutics: Exemplified by Chaihu-Shugan-San for chronic atrophic gastritis
Manuscript Source Invited Manuscript
All Author List Yan Pan and Fu-Yong Jiao
ORCID
Author(s) ORCID Number
Yan Pan http://orcid.org/0000-0003-0240-7085
Fu-Yong Jiao http://orcid.org/0000-0002-8306-2543
Funding Agency and Grant Number
Corresponding Author Fu-Yong Jiao, MD, PhD, Shaanxi Kawasaki Disease Diagnosis and Treatment Center, Children’s Hospital, Shaanxi Provincial People’s Hospital, Xi’an Jiaotong University, No. 256 Youyi West Road, Beilin District, Xi’an 710000, Shaanxi Province, China. 3105089948@qq.com
Key Words Chronic atrophic gastritis; Chaihu-Shugan-San; Network pharmacology; Nuclear factor-kappa B; Gut microbiota; Integrative medicine; Translational research
Core Tip This paper emphasizes that the research of song et al is an example of the integrated research of gastroenterology. Through the combination of network pharmacology, experimental validation and microbiome analysis, this study clarified how Chaihu-Shugan-San can improve chronic atrophic gastritis by double inhibiting inflammation and apoptosis driven by nuclear factor kappaB, and regulating intestinal flora. This paper critically evaluates this methodology as a blueprint for future research on complex botanical drugs, and emphasizes the need for subsequent clinical trials, standardization of phytochemistry, and the development of integrated biomarker groups, in order to translate these mechanistic insights into personalized clinical practice for precancerous lesions.
Publish Date 2026-08-11 06:12
Citation

Pan Y, Jiao FY. Letter to the Editor: Integrative mechanistic exploration in gastrointestinal therapeutics: Exemplified by Chaihu-Shugan-San for chronic atrophic gastritis. World J Gastroenterol 2026; 32(33): 118981

URL https://www.wjgnet.com/1007-9327/full/v32/i33/118981.htm
DOI https://doi.org/10.3748/wjg.118981
Full Article (PDF) WJG-32-118981-with-cover.pdf
Manuscript File 118981_Auto_Edited_013815.docx
Answering Reviewers 118981-answering-reviewers.pdf
Audio Core Tip 118981-audio.mp3
Conflict-of-Interest Disclosure Form 118981-conflict-of-interest-statement.pdf
Copyright License Agreement 118981-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 118981-non-native-speakers.pdf
Peer-review Report 118981-peer-reviews.pdf
Scientific Misconduct Check 118981-scientific-misconduct-check.png
Scientific Editor Work List 118981-scientific-editor-work-list.pdf
CrossCheck Report 118981-crosscheck-report.pdf