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7/14/2026 9:35:00 AM | Browse: 3 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 118993
Country China
Received
2026-01-16 05:57
Peer-Review Started
2026-01-16 05:58
First Decision by Editorial Office Director
2026-01-23 10:08
Return for Revision
2026-01-23 10:08
Revised
2026-01-28 14:18
Publication Fee Transferred
Second Decision by Editor
2026-03-02 02:48
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-03-02 07:38
Articles in Press
2026-03-02 07:38
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-07-06 01:39
Publish the Manuscript Online
2026-07-14 09:35
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Correspondence
Article Title Letter to the Editor: Probiotics counteract polyethylene glycol bowel preparation dysbiosis and infection risk
Manuscript Source Invited Manuscript
All Author List Yang Fu
ORCID
Author(s) ORCID Number
Yang Fu http://orcid.org/0000-0003-2714-674X
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China No. 82300731
Corresponding Author Yang Fu, PhD, Department of Gastroenterology, Institute of Pancreatic Diseases, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 650 Songjiang Road, Shanghai 201600, China. yzfuyang3341@163.com
Key Words Polyethylene glycol; Bowel preparation; Dysbiosis; Citrobacter rodentium; Probiotics; Colonoscopy; Infection risk
Core Tip Polyethylene glycol bowel preparation can transiently disrupt gut microbiota and weaken colonization resistance, potentially increasing susceptibility to enteric infections. Kou et al provide mechanistic evidence that polyethylene glycol creates a 14-day vulnerability window in which Citrobacter rodentium colonization, virulence, and colitis severity are amplified in a microbiota-dependent manner. Importantly, Lactobacillus acidophilus supplementation restores microbial balance and reduces infection severity, supporting microbiota-protective strategies. These findings, together with real-world data showing non-negligible post-colonoscopy infection visits, argue for risk stratification and microbiota-sparing adjuncts in high-risk patients.
Publish Date 2026-07-14 09:35
Citation

Fu Y. Letter to the Editor: Probiotics counteract polyethylene glycol bowel preparation dysbiosis and infection risk. World J Gastroenterol 2026; 32(28): 118993

URL https://www.wjgnet.com/1007-9327/full/v32/i28/118993.htm
DOI https://doi.org/10.3748/wjg.118993
Full Article (PDF) WJG-32-118993-with-cover.pdf
Manuscript File 118993_Auto_Edited_071117.docx
Answering Reviewers 118993-answering-reviewers.pdf
Audio Core Tip 118993-audio.mp3
Conflict-of-Interest Disclosure Form 118993-conflict-of-interest-statement.pdf
Copyright License Agreement 118993-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 118993-non-native-speakers.pdf
Peer-review Report 118993-peer-reviews.pdf
Scientific Misconduct Check 118993-scientific-misconduct-check.png
Scientific Editor Work List 118993-scientific-editor-work-list.pdf
CrossCheck Report 118993-crosscheck-report.pdf