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Publication Name World Journal of Gastroenterology
Manuscript ID 119006
Country China
Received
2026-01-29 03:35
Peer-Review Started
2026-01-29 03:35
First Decision by Editorial Office Director
2026-02-13 08:20
Return for Revision
2026-02-13 08:20
Revised
2026-02-27 05:35
Publication Fee Transferred
2026-03-03 14:35
Second Decision by Editor
2026-03-18 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-03-18 05:45
Articles in Press
2026-03-18 05:45
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-06-03 00:46
Publish the Manuscript Online
2026-06-12 10:39
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Case Report
Article Title Chronic ulcer diagnosis and perforation risk with oral agent contrast-enhanced ultrasound: A case report and review of literature
Manuscript Source Unsolicited Manuscript
All Author List Man-Li Wei and Qing-Lan Tan
ORCID
Author(s) ORCID Number
Man-Li Wei http://orcid.org/0009-0005-2431-3575
Funding Agency and Grant Number
Funding Agency Grant Number
Youth Fund for Self-Financed Scientific Research Projects of the Guangxi Zhuang Autonomous Region Health Commission Z20190921
Corresponding Author Man-Li Wei, Associate Chief Physician, Department of Ultrasound Medicine, The First People's Hospital of Nanning, No. 89, Qixing Road, Qingxiu District, Nanning 530021, Guangxi Zhuang Autonomous Region, China. 260077529@qq.com
Key Words Gastric ulcer; Multidisciplinary treatment; Hepatocellular carcinoma; Oral agent; Ultrasound; Perforation; Case report
Core Tip Gastric perforation is a rare yet severe complication of abdominal radiotherapy, occurring more frequently when combined immunotherapy and tyrosine kinase inhibitor therapy are administered. Most patients require emergency surgical intervention. This study reports a case where, within the complex context of comprehensive hepatocellular carcinoma treatment (involving radiotherapy, chemotherapy, immunotherapy, and targeted therapy), traditional methods (gastroscopy, contrast-enhanced computed tomography) could not accurately assess ulcer infiltration depth due to blood crust coverage and gastric wall edema. Oral agent contrast-enhanced ultrasound as a novel monitoring tool, clearly demonstrated that the ulcer had reached the serosal layer, thereby successfully predicting impending perforation.
Publish Date 2026-06-12 10:39
Citation

Wei ML, Tan QL. Chronic ulcer diagnosis and perforation risk with oral agent contrast-enhanced ultrasound: A case report and review of literature. World J Gastroenterol 2026; 32(24): 119006

URL https://www.wjgnet.com/1007-9327/full/v32/i24/119006.htm
DOI https://doi.org/10.3748/wjg.119006
Full Article (PDF) WJG-32-119006-with-cover.pdf
CARE Checklist–2016 119006-CARE-Checklist-2016.pdf
Manuscript File 119006_Auto_Edited_071624.docx
Answering Reviewers 119006-answering-reviewers.pdf
Audio Core Tip 119006-audio.mp3
Conflict-of-Interest Disclosure Form 119006-conflict-of-interest-statement.pdf
Copyright License Agreement 119006-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 119006-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 119006-non-native-speakers.pdf
Video 119006-video.mp4
Peer-review Report 119006-peer-reviews.pdf
Scientific Misconduct Check 119006-scientific-misconduct-check.png
Scientific Editor Work List 119006-scientific-editor-work-list.pdf
CrossCheck Report 119006-crosscheck-report.pdf