BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
6/24/2026 9:14:00 AM | Browse: 0 | Download: 0
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 119023
Country Italy
Received
2026-01-28 03:44
Peer-Review Started
2026-01-28 03:45
First Decision by Editorial Office Director
2026-02-13 08:18
Return for Revision
2026-02-13 14:41
Revised
2026-02-27 10:17
Publication Fee Transferred
Second Decision by Editor
2026-03-26 02:33
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-03-26 07:10
Articles in Press
2026-03-26 07:10
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-05-28 02:19
Publish the Manuscript Online
2026-06-24 09:14
ISSN 1948-9366 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Transplantation
Manuscript Type Minireviews
Article Title Combined liver-kidney transplantation in polycystic disease: Our experience and literature review
Manuscript Source Invited Manuscript
All Author List Alessandro Tropea, Duilio Pagano, Salvatore Piazza, Sergio Calamia, Sergio Li Petri, Fabrizio di Francesco, Pasquale Bonsignore, Irene Vitale, Ivan Vella, Caterina Accardo, Federica Chimenti, Paola Salis, Barbara Buscemi, Xing Lai, Alessandro Mattina and Salvatore Gruttadauria
ORCID
Author(s) ORCID Number
Alessandro Tropea http://orcid.org/0000-0001-6767-6679
Duilio Pagano http://orcid.org/0000-0003-3987-9262
Sergio Calamia http://orcid.org/0000-0002-8594-0071
Sergio Li Petri http://orcid.org/0000-0003-1675-1469
Fabrizio di Francesco http://orcid.org/0000-0003-3473-2544
Pasquale Bonsignore http://orcid.org/0000-0002-3118-5453
Ivan Vella http://orcid.org/0000-0002-4946-512X
Caterina Accardo http://orcid.org/0000-0003-3497-683X
Federica Chimenti http://orcid.org/0000-0002-6415-8750
Barbara Buscemi http://orcid.org/0009-0007-6560-2589
Xing Lai http://orcid.org/0000-0002-2543-816X
Alessandro Mattina http://orcid.org/0000-0003-3458-0894
Salvatore Gruttadauria http://orcid.org/0000-0002-9684-8035
Funding Agency and Grant Number
Corresponding Author Alessandro Tropea, MD, PhD, Abdominal Center, IRCCS ISMETT, Via E. Tricomi, 5, Palermo 90127, Italy. atropea@ismett.edu
Key Words Combined liver-kidney transplantation; Liver transplant; Hypothermic machine perfusion; Polycistic disease; End-stage renal disease; Chronic liver disease; Cirrhosis
Core Tip Polycystic liver–kidney disease is a rare but debilitating condition requiring combined liver–kidney transplantation (CLKT). This evidence review integrates contemporary data with our single-centre series (ISMETT, 2008–2025) of 20 CLKTs for polycystic disease. The results show 95% patient survival (95% C.I.: 86─100%) at 1, 3, and 5 years after transplant and two lost kidney graft. We summarise actionable selection and technical considerations, such as symptom-driven liver listing, renal trajectory, and selective native nephrectomy, and emphasise innovations including liver-mediated immunoprotection and hypothermic machine perfusion, which enable delayed kidney implantation and the safer use of extended-criteria donors.
Publish Date 2026-06-24 09:14
Citation

Tropea A, Pagano D, Piazza S, Calamia S, Li Petri S, di Francesco F, Bonsignore P, Vitale I, Vella I, Accardo C, Chimenti F, Salis P, Buscemi B, Lai X, Mattina A, Gruttadauria S. Combined liver-kidney transplantation in polycystic disease: Our experience and literature review. World J Gastrointest Surg 2026; 18(6): 119023
URL https://www.wjgnet.com/1948-9366/full/v18/i6/119023.htm
DOI https://doi.org/10.4240/wjgs.119023
Full Article (PDF) WJGS-18-119023-with-cover.pdf
Manuscript File 119023_Auto_Edited_091832.docx
Answering Reviewers 119023-answering-reviewers.pdf
Audio Core Tip 119023-audio.m4a
Conflict-of-Interest Disclosure Form 119023-conflict-of-interest-statement.pdf
Copyright License Agreement 119023-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 119023-non-native-speakers.pdf
Peer-review Report 119023-peer-reviews.pdf
Scientific Misconduct Check 119023-scientific-misconduct-check.png
Scientific Editor Work List 119023-scientific-editor-work-list.pdf
CrossCheck Report 119023-crosscheck-report.pdf
Write to the Help Desk
All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.