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9/1/2026 4:34:36 AM | Browse: 0 | Download: 0
Publication Name World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID 119031
Country India
Received
2026-01-19 02:38
Peer-Review Started
2026-01-19 02:41
First Decision by Editorial Office Director
2026-02-12 08:29
Return for Revision
2026-02-12 08:29
Revised
2026-02-25 07:09
Publication Fee Transferred
Second Decision by Editor
2026-05-13 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-05-13 07:09
Articles in Press
2026-05-13 07:09
Edit the Manuscript by Language Editor
2026-05-16 01:16
Typeset the Manuscript
2026-08-26 01:13
Publish the Manuscript Online
2026-09-01 04:34
ISSN 2150-5349 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Infectious Diseases
Manuscript Type Opinion Review
Article Title Beyond the Gut microbe: rethinking infection, microbiome harmony, and the one-health continuum
Manuscript Source Invited Manuscript
All Author List Sumit Rai and Prasan Kumar Panda
ORCID
Author(s) ORCID Number
Prasan Kumar Panda http://orcid.org/0000-0002-3008-7245
Funding Agency and Grant Number
Corresponding Author Prasan Kumar Panda, Professor, Internal Medicine (ID Division), All India Institute of Medical Sciences, Room No. 409, College Block, Rishikesh 249203, Uttarākhand, India. motherprasanna@rediffmail.com
Key Words Microbiome; Pathobiome; Diagnostic stewardship; One Health; Pathogen identification
Core Tip Advances in culture and sequencing have expanded microbial detection, but presence does not equal pathogenicity. Many infections reflect disruption of the human microbiome rather than invasion by a novel pathogen. Misinterpretation of isolates drives antimicrobial misuse, resistance, and ecological harm. This opinion proposes an eight-question, clinically grounded framework to distinguish pathogens from non-pathogens by integrating host site and response, ecological context, contamination assessment, and transparent reporting. Applying this approach aligns infectious-disease practice with diagnostic stewardship, one health principles, and preservation of microbial harmony from individual patients to planetary health.
Publish Date 2026-09-01 04:34
Citation

Rai S, Panda PK. Beyond the Gut microbe: rethinking infection, microbiome harmony, and the one-health continuum. World J Gastrointest Pharmacol Ther 2026; 17(3): 119031

URL https://www.wjgnet.com/2150-5349/full/v17/i3/119031.htm
DOI https://doi.org/10.4292/wjgpt.119031
Full Article (PDF) WJGPT-17-119031-with-cover.pdf
Manuscript File 119031_Auto_Edited_013113.docx
Answering Reviewers 119031-answering-reviewers.pdf
Audio Core Tip 119031-audio.mp3
Conflict-of-Interest Disclosure Form 119031-conflict-of-interest-statement.pdf
Copyright License Agreement 119031-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 119031-non-native-speakers.pdf
Peer-review Report 119031-peer-reviews.pdf
Scientific Misconduct Check 119031-scientific-misconduct-check.png
CrossCheck Report 119031-crosscheck-report.pdf