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9/1/2026 6:22:37 AM | Browse: 1 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 119058
Country China
Received
2026-01-19 02:12
Peer-Review Started
2026-01-19 02:14
First Decision by Editorial Office Director
2026-01-29 09:24
Return for Revision
2026-01-29 09:24
Revised
2026-02-02 08:16
Publication Fee Transferred
Second Decision by Editor
2026-02-27 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-27 07:47
Articles in Press
2026-02-27 07:47
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-08-24 09:11
Publish the Manuscript Online
2026-09-01 06:22
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Editorial
Article Title Novel regulatory network of the TGF-β/ZEB1/LMO7 axis in colorectal cancer metastasis
Manuscript Source Invited Manuscript
All Author List Xia Yao, Xue-Yuan Hu, Hong-Fei Tan, Jing-Feng Tang, Rui Zhang and Ce-Fan Zhou
ORCID
Author(s) ORCID Number
Ce-Fan Zhou http://orcid.org/0000-0003-0680-3843
Funding Agency and Grant Number
Funding Agency Grant Number
National Key Research and Development Program of China 2023YFC2507904
National Natural Science Foundation of China 32270768, 82273970
Innovation Group Project of Hubei Province 2023AFA026
The Key Cultivation Project of Hubei Province for Science and Technology 2024DJA037
National Natural Science Foundation of Hubei 2025AFA085
Corresponding Author Ce-Fan Zhou, Professor, School of Life and Health Sciences, Institute of Biomedical Research, National “111” Center for Cellular Regulation and Molecular Pharmaceutics, Key Laboratory of Fermentation Engineering (Ministry of Education), Hubei University of Technology, No. 28 Nanli Road, Wuhan 430068, Hubei Province, China. cefan@hbut.edu.cn
Key Words LIM domain only protein 7; Colorectal cancer; Epithelial-mesenchymal transition; Transforming growth factor-β; Zinc finger E-box binding homeobox 1
Core Tip Bai et al identified the transforming growth factor-β/zinc finger E-box binding homeobox 1/LIM domain only protein 7 (LMO7) axis in colorectal cancer. Their work establishes LMO7 as a key downstream effector of this axis, showing that it significantly promotes colorectal cancer cell proliferation, migration, invasion, and metastasis in vivo. Significantly, LMO7 expression correlates positively with adverse clinicopathological features. Based on this foundational discovery, future research will further investigate the functional implications of LMO7’s subcellular localization, the regulatory dynamics of this pathway, and the identity of its downstream effector molecules. Such efforts are crucial for constructing a more comprehensive molecular framework.
Publish Date 2026-09-01 06:22
Citation

Yao X, Hu XY, Tan HF, Tang JF, Zhang R, Zhou CF. Novel regulatory network of the TGF-β/ZEB1/LMO7 axis in colorectal cancer metastasis. World J Gastroenterol 2026; 32(37): 119058

URL https://www.wjgnet.com/1007-9327/full/v32/i37/119058.htm
DOI https://doi.org/10.3748/wjg.119058
Full Article (PDF) WJG-32-119058-with-cover.pdf
Manuscript File 119058_Auto_Edited_070402.docx
Answering Reviewers 119058-answering-reviewers.pdf
Audio Core Tip 119058-audio.mp3
Conflict-of-Interest Disclosure Form 119058-conflict-of-interest-statement.pdf
Copyright License Agreement 119058-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 119058-non-native-speakers.pdf
Peer-review Report 119058-peer-reviews.pdf
Scientific Misconduct Check 119058-scientific-misconduct-check.png
CrossCheck Report 119058-crosscheck-report.pdf