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Articles Published Processes
7/17/2026 8:23:32 AM | Browse: 2 | Download: 0
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Received |
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2026-01-26 06:53 |
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Peer-Review Started |
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2026-01-26 06:54 |
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First Decision by Editorial Office Director |
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2026-02-09 09:47 |
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Return for Revision |
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2026-02-09 09:47 |
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Revised |
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2026-02-18 16:55 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-04-07 02:44 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-04-07 10:15 |
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Articles in Press |
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2026-04-07 10:15 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-07-06 02:53 |
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Publish the Manuscript Online |
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2026-07-17 08:23 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Correspondence |
| Article Title |
Letter to the Editor: Precise phenotyping clarifies uric acid-to-high-density lipoprotein cholesterol ratio for cardiovascular risk in metabolic dysfunction-associated steatotic liver disease
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Peng-Mei Zhou, Chao-Ting Yang, Jian-Feng Bao and Jin-Song Huang |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Jin-Song Huang, Department of Hepatology, Hangzhou Xixi Hospital Affiliated to Zhejiang Chinese Medical University, No. 2 Hengbu Road, Hangzhou 310023, Zhejiang Province, China. huangjinsongyz@126.com |
| Key Words |
Metabolic dysfunction-associated steatotic liver disease; Cardiovascular risk; Uric acid-to-high-density lipoprotein cholesterol ratio; Phenotypic heterogeneity; Risk stratification; Noninvasive assessment |
| Core Tip |
The diagnosis of ultrasonography-based metabolic dysfunction-associated steatotic liver disease overlooks hepatic phenotypic heterogeneity and the shared inflammatory metabolic mechanisms of the cardiohepatic axis, potentially confounding the association between uric acid-to-high-density lipoprotein cholesterol ratio (UHR) and cardiovascular disease risk. We argue that precise phenotyping, namely quantification of steatosis using the controlled attenuation parameter or magnetic resonance imaging proton-density fat fraction and staging fibrosis using vibration-controlled transient elastography, is essential to determine whether UHR is an independent predictor of cardiovascular disease risk, thereby clarifying whether UHR is a general biomarker or an indicator of high-risk patients requiring integrated cardiometabolic–hepatic management. |
| Publish Date |
2026-07-17 08:23 |
| Citation |
Zhou PM, Yang CT, Bao JF, Huang JS. Letter to the Editor: Precise phenotyping clarifies uric acid-to-high-density lipoprotein cholesterol ratio for cardiovascular risk in metabolic dysfunction-associated steatotic liver disease. World J Gastroenterol 2026; 32(29): 119060
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| URL |
https://www.wjgnet.com/1007-9327/full/v32/i29/119060.htm |
| DOI |
https://doi.org/10.3748/wjg.119060 |
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