| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Baseline multimodal clinical-radiomics-pathomics model predicts mucosal healing in Crohn’s disease after infliximab therapy
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Han Zhang, Hui-Min Liu, Jia-Xin Pei, Jing Hu, Chao Zhu, Kai-Cai Liu, Chang Rong, Xiao-Min Zheng, Yi Shen, Yong-Ping Cai and Xing-Wang Wu |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Research Fund of Anhui Institute of Translational Medicine |
No. 2023zhyx-C35 |
| Natural Science Foundation of Anhui Province, China |
No. 2308085MH241 |
|
| Corresponding Author |
Xing-Wang Wu, Department of Radiology, The First Affiliated Hospital of Anhui Medical University, Intersection of Tianhai Road and Feicui Road, Feixi County, Hefei 230022, Anhui Province, China. wuxingwang@ahmu.edu.cn |
| Key Words |
Crohn disease; Mucosal healing; Radiomics; Pathomics; Infliximab |
| Core Tip |
In response to the clinical requirement for an accurate, noninvasive predictive instrument for mucosal healing (MH) in Crohn’s disease (CD), this research endeavors to develop and validate a multimodal integrated model. The combined radiomics-pathomics model forecasts MH in ileal/ileocolonic CD, with area under the curve values of 0.915/0.922, surpassing those of other models. It offers a noninvasive, precise means for predicting MH in CD patients, thereby promoting personalized clinical decision-making and enhancing patient prognoses. |
| Publish Date |
2026-06-30 13:35 |
| Citation |
Zhang H, Liu HM, Pei JX, Hu J, Zhu C, Liu KC, Rong C, Zheng XM, Shen Y, Cai YP, Wu XW. Baseline multimodal clinical-radiomics-pathomics model predicts mucosal healing in Crohn’s disease after infliximab therapy. World J Gastroenterol 2026; 32(25): 119071
|
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i25/119071.htm |
| DOI |
https://doi.org/10.3748/wjg.119071 |
