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Articles Published Processes
9/9/2026 9:45:10 AM | Browse: 2 | Download: 0
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Received |
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2026-01-26 06:26 |
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Peer-Review Started |
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2026-01-26 06:26 |
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First Decision by Editorial Office Director |
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2026-03-13 10:20 |
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Return for Revision |
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2026-03-13 13:43 |
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Revised |
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2026-03-28 15:43 |
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Publication Fee Transferred |
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2026-05-18 03:57 |
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Second Decision by Editor |
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2026-05-14 02:46 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-05-14 03:46 |
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Articles in Press |
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2026-05-14 03:46 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-08-20 08:12 |
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Publish the Manuscript Online |
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2026-09-09 09:45 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Pathological characteristics of hepatocellular carcinoma: A dual-center correlation analysis and validation
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hai-Bo Huang, Ying-Dan Zhang, Jie Yang, Ying-Ying Huang, Li-Feng Huang, Shuang-Yue Wang, Wei Lu, Ze-He Huang and Ke Ding |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Self-raised Research Projects from the Health Commission of Guangxi Zhuang Autonomous Region, China |
No. Z20200953 |
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| Corresponding Author |
Ke Ding, Department of Radiology, The Third Affiliated Hospital of Guangxi Medical University, No. 13 Dancun Road, Nanning 530031, Guangxi Zhuang Autonomous Region, China. 272480365@qq.com |
| Key Words |
Hepatocellular carcinoma; Edmondson-Steiner grading; Ki-67; Microvascular invasion; Satellite nodule; Biomarker |
| Core Tip |
This dual-center retrospective study validates a tightly linked aggressive pathological cluster (Edmondson grade, microvascular invasion, satellite nodules, Ki-67) in hepatocellular carcinoma. We identify Ki-67 as a core, reproducible biomarker, with a validated cutoff of 32.5% demonstrating high specificity (0.813) for predicting satellite nodules positivity across two independent centers. These findings provide multicenter pathological evidence to inform postoperative risk stratification and adjuvant therapy decisions. |
| Publish Date |
2026-09-09 09:45 |
| Citation |
Huang HB, Zhang YD, Yang J, Huang YY, Huang LF, Wang SY, Lu W, Huang ZH, Ding K. Pathological characteristics of hepatocellular carcinoma: A dual-center correlation analysis and validation. World J Gastrointest Oncol 2026; 18(9): 119082
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| URL |
https://www.wjgnet.com/1948-5204/full/v18/i9/119082.htm |
| DOI |
https://doi.org/10.4251/wjgo.119082 |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
