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Articles Published Processes
4/9/2026 3:52:16 AM | Browse: 2 | Download: 13
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Received |
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2026-01-23 03:00 |
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Peer-Review Started |
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2026-01-23 03:19 |
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First Decision by Editorial Office Director |
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2026-02-13 07:28 |
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Return for Revision |
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2026-02-13 07:28 |
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Revised |
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2026-02-21 12:13 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-03-09 02:39 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-03-09 04:19 |
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Articles in Press |
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2026-03-09 04:19 |
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Edit the Manuscript by Language Editor |
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2026-03-14 21:04 |
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Typeset the Manuscript |
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2026-03-30 02:33 |
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Publish the Manuscript Online |
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2026-04-09 03:52 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Report |
| Article Title |
Herpes simplex encephalitis associated with infliximab therapy for ulcerative colitis: A case report
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Maryam Aleissa, Saleh A Busbait, Ryba Bhullar, Jai P Singh, Jasneet S Bhullar and Vijay K Mittal |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Jasneet S Bhullar, FACS, FASCRS, MD, Department of Surgery, Henry Ford Providence Hospital, Michigan State University College of Human Medicine, 16001 W Nine Mile Rd, Southfield, MI 48075, United States. drjsbhullar@gmail.com |
| Key Words |
Herpes simplex encephalitis; TNF inhibitor; Ulcerative colitis; Encephalitis; Herpes simplex virus; Case report |
| Core Tip |
Herpes simplex encephalitis is a rare but potentially fatal complication of tumor necrosis factor-alpha (TNF-α) inhibitor therapy. This case presents a rare instance of herpes simplex virus type 1 encephalitis, which developed only a few days after starting infliximab treatment for ulcerative colitis. Published literature provides evidence that TNF-α functions as a vital factor that protects against viral infections in the nervous system. Inhibition of TNF-α action allows viruses to reactivate and enter the brain. The treatment of herpes simplex encephalitis requires early recognition and an immediate cerebrospinal fluid polymerase chain reaction sample and initiation of antiviral medication to achieve better neurological results. |
| Publish Date |
2026-04-09 03:52 |
| Citation |
Aleissa M, Busbait SA, Bhullar R, Singh JP, Bhullar JS, Mittal VK. Herpes simplex encephalitis associated with infliximab therapy for ulcerative colitis: A case report. World J Clin Cases 2026; 14(11): 119107 |
| URL |
https://www.wjgnet.com/2307-8960/full/v14/i11/119107.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v14.i11.119107 |
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