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5/19/2026 7:13:10 AM | Browse: 1 | Download: 0
Publication Name World Journal of Cardiology
Manuscript ID 119108
Country Italy
Received
2026-01-19 01:31
Peer-Review Started
2026-01-19 01:32
First Decision by Editorial Office Director
2026-02-03 09:43
Return for Revision
2026-02-03 09:43
Revised
2026-02-17 22:33
Publication Fee Transferred
Second Decision by Editor
2026-04-23 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-04-23 09:58
Articles in Press
2026-04-23 09:58
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-05-09 09:26
Publish the Manuscript Online
2026-05-19 07:13
ISSN 1949-8462 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cardiac & Cardiovascular Systems
Manuscript Type Review
Article Title Mental stress: A novel cardiovascular risk factor
Manuscript Source Invited Manuscript
All Author List Maurizio Giuseppe Abrignani, Nicolò Renda, Vincenzo Abrignani, Alberto Lombardo and Fabiana Lucà
ORCID
Author(s) ORCID Number
Maurizio Giuseppe Abrignani http://orcid.org/0000-0002-0237-7157
Nicolò Renda http://orcid.org/0000-0002-8785-0627
Vincenzo Abrignani http://orcid.org/0000-0002-7035-8900
Alberto Lombardo http://orcid.org/0000-0002-4527-2507
Fabiana Lucà http://orcid.org/0000-0002-5369-5382
Funding Agency and Grant Number
Corresponding Author Maurizio Giuseppe Abrignani, MD, Operative Unit of Cardiology, P. Borsellino Hospital, ASP Trapani, 175 Via Salemi, Marsala 91025, Trapani, Italy. maur.abri@alice.it
Key Words Stress; Cardiovascular diseases; Risk factors; Epidemiology; Prevention
Core Tip Many acute coronary syndromes and strokes occur in patients without traditional risk factors. This highlights the growing importance of psychosocial factors, especially mental stress, as recognized by recent guidelines. Acute stress can trigger severe cardiovascular (CV) events, while chronic stress - often linked to ongoing personal or professional issues - promotes inflammation and endothelial dysfunction, contributing to atherosclerosis. Mental stress tests can induce transient myocardial ischemia even without significant coronary obstruction. Therapeutic strategies targeting stress reduction may help lower CV risk. This narrative review synthesizes epidemiological data and explores potential mechanisms regarding interactions between stress and CV disease, outlining future research directions.
Publish Date 2026-05-19 07:13
Citation

Abrignani MG, Renda N, Abrignani V, Lombardo A, Lucà F. Mental stress: A novel cardiovascular risk factor. World J Cardiol 2026; 18(5): 119108

URL https://www.wjgnet.com/1949-8462/full/v18/i5/119108.htm
DOI https://dx.doi.org/10.4330/wjc.v18.i5.119108
Full Article (PDF) WJC-18-119108-with-cover.pdf
Manuscript File 119108_Auto_Edited_090149.docx
Answering Reviewers 119108-answering-reviewers.pdf
Audio Core Tip 119108-audio.mp3
Conflict-of-Interest Disclosure Form 119108-conflict-of-interest-statement.pdf
Copyright License Agreement 119108-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 119108-non-native-speakers.pdf
Peer-review Report 119108-peer-reviews.pdf
Scientific Misconduct Check 119108-scientific-misconduct-check.png
Scientific Editor Work List 119108-scientific-editor-work-list.pdf
CrossCheck Report 119108-crosscheck-report.pdf