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Articles Published Processes
9/9/2026 9:45:09 AM | Browse: 2 | Download: 0
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Received |
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2026-01-20 03:27 |
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Peer-Review Started |
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2026-01-20 05:45 |
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First Decision by Editorial Office Director |
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2026-02-02 08:56 |
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Return for Revision |
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2026-02-02 08:56 |
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Revised |
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2026-03-13 11:59 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-06-16 02:33 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-06-16 07:22 |
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Articles in Press |
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2026-06-16 07:22 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-08-24 00:26 |
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Publish the Manuscript Online |
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2026-09-09 09:45 |
| ISSN |
1948-5204 (online) |
| Open Access |
Open-Access: This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Association between lymphopenia and the survival of patients with colorectal cancer: A meta-analysis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Kai Chen, Hang Li and Han-He Chen |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Kai Chen, Researcher, Department of Gastrointestinal Surgery, The Affiliated Hospital of Putian University, No. 999 Dongzhen East Road, Licheng District, Putian 351100, Fujian Province, China. chenkaipt@163.com |
| Key Words |
Colorectal cancer; Lymphopenia; Absolute lymphocyte count; Survival; Progression; Meta-analysis |
| Core Tip |
This meta-analysis synthesized evidence from 13 retrospective cohort studies involving 3383 patients with colorectal cancer (CRC) to clarify the prognostic significance of lymphopenia. Both pretreatment and treatment-related lymphopenia were significantly associated with poorer progression-free and overall survival. Notably, treatment-related lymphopenia and lower absolute lymphocyte count cutoffs showed stronger associations with disease progression. These findings highlight lymphopenia as a simple, readily available immune biomarker for risk stratification and prognosis assessment in CRC, supporting closer lymphocyte monitoring during clinical management. |
| Publish Date |
2026-09-09 09:45 |
| Citation |
Chen K, Li H, Chen HH. Association between lymphopenia and the survival of patients with colorectal cancer: A meta-analysis. World J Gastrointest Oncol 2026; 18(9): 119140
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| URL |
https://www.wjgnet.com/1948-5204/full/v18/i9/119140.htm |
| DOI |
https://doi.org/10.4251/wjgo.119140 |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
