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Publication Name World Journal of Diabetes
Manuscript ID 119178
Country United Kingdom
Received
2026-01-21 00:24
Peer-Review Started
2026-01-29 09:14
First Decision by Editorial Office Director
2026-03-05 08:51
Return for Revision
2026-03-05 08:51
Revised
2026-03-29 17:29
Publication Fee Transferred
Second Decision by Editor
2026-05-06 03:20
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-05-06 06:26
Articles in Press
2026-05-06 06:26
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-06-02 03:16
Publish the Manuscript Online
2026-06-11 11:23
ISSN 1948-9358 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Opinion Review
Article Title Helicobacter pylori and diabetic complications: Stronger evidence for the interlink
Manuscript Source Invited Manuscript
All Author List Sanja Medenica, Cornelius J Fernandez and Joseph M Pappachan
ORCID
Author(s) ORCID Number
Sanja Medenica http://orcid.org/0000-0002-6241-3033
Cornelius J Fernandez http://orcid.org/0000-0002-1171-5525
Joseph M Pappachan http://orcid.org/0000-0003-0886-5255
Funding Agency and Grant Number
Corresponding Author Joseph M Pappachan, FRCP, MD, MRCP, Professor, Senior Researcher, Faculty of Science, Manchester Metropolitan University, All Saints Campus, Grosvenor Square, Manchester M15 6BH, Greater Manchester, United Kingdom. drpappachan@yahoo.co.in
Key Words Autoimmune disorders; Helicobacter pylori; Metabolic dysregulation; Type 1 diabetes mellitus; Type 2 diabetes mellitus
Core Tip Helicobacter pylori (H. pylori) infection is increasingly recognized as a systemic disease with important metabolic consequences. Growing evidence supports a bidirectional relationship between H. pylori infection and DM, particularly T2DM, in which chronic inflammation, insulin resistance, and immune dysregulation play central roles. Patients with DM and concomitant H. pylori infection appear to have a higher risk of gastrointestinal, hepatic, and renal complications. Recent experimental data further strengthen this association by demonstrating aggravated organ damage in diabetic models with H. pylori infection. Recognition of this interlink has important implications for screening, monitoring, and therapeutic strategies in patients with diabetes.
Publish Date 2026-06-11 11:23
Citation

Medenica S, Fernandez CJ, Pappachan JM. Helicobacter pylori and diabetic complications: Stronger evidence for the interlink. World J Diabetes 2026; 17(6): 119178

URL https://www.wjgnet.com/1948-9358/full/v17/i6/119178.htm
DOI https://doi.org/10.4239/wjd.119178
Full Article (PDF) WJD-17-119178-with-cover.pdf
Manuscript File 119178_Auto_Edited_083235.docx
Answering Reviewers 119178-answering-reviewers.pdf
Audio Core Tip 119178-audio.m4a
Conflict-of-Interest Disclosure Form 119178-conflict-of-interest-statement.pdf
Copyright License Agreement 119178-copyright-assignment.pdf
Peer-review Report 119178-peer-reviews.pdf
Scientific Misconduct Check 119178-scientific-misconduct-check.png
Scientific Editor Work List 119178-scientific-editor-work-list.pdf
CrossCheck Report 119178-crosscheck-report.pdf