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Articles Published Processes
6/12/2026 10:39:43 AM | Browse: 0 | Download: 0
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Received |
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2026-01-22 06:16 |
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Peer-Review Started |
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2026-01-22 06:17 |
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First Decision by Editorial Office Director |
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2026-02-04 10:06 |
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Return for Revision |
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2026-02-04 10:06 |
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Revised |
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2026-02-12 17:27 |
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Publication Fee Transferred |
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2026-02-13 09:18 |
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Second Decision by Editor |
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2026-03-12 02:36 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-03-12 08:44 |
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Articles in Press |
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2026-03-12 08:44 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-06-02 00:18 |
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Publish the Manuscript Online |
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2026-06-12 10:39 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Surgery |
| Manuscript Type |
Case Report |
| Article Title |
Successful conversion therapy for advanced hepatocellular carcinoma with biliary tumor thrombus and bilateral lobe involvement: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yu Zhang, Lu-Yang Zhang, Bo Meng, Yun-Jian Wang, Nan-Mu Yang, Qiong Li and Min Zhang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Henan Province Science and Technology Research Project |
SBGJ202103035 |
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| Corresponding Author |
Min Zhang, MD, PhD, Vice Director, Department of Hepatobiliary and Pancreatic Surgery, The Affiliated Cancer Hospital of Zhengzhou University, No.127, Dongming Road, 450008, Zhengzhou, China, Zhengzhou 450008, Henan Province, China. zhangyuu2022@gs.zzu.edu.cn |
| Key Words |
Hepatocellular carcinoma; Hepatocellular carcinoma-derived biliary tumor thrombus; Conversion therapy; Immunotherapy; Targeted therapy; Case report |
| Core Tip |
For advanced bilateral multilobular hepatocellular carcinoma (HCC) with HCC-derived biliary tumor thrombus, conversion therapy using camrelizumab (immunotherapy) combined with apatinib mesylate (targeted therapy) and hepatic radiofrequency ablation successfully reduced tumor burden and eliminated the biliary tumor thrombus, enabling radical surgical resection. This approach resulted in short-term disease-free survival (6 months after surgery) with preserved normal liver function. |
| Publish Date |
2026-06-12 10:39 |
| Citation |
Zhang Y, Zhang LY, Meng B, Wang YJ, Yang NM, Li Q, Zhang M. Successful conversion therapy for advanced hepatocellular carcinoma with biliary tumor thrombus and bilateral lobe involvement: A case report. World J Gastroenterol 2026; 32(24): 119220
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| URL |
https://www.wjgnet.com/1007-9327/full/v32/i24/119220.htm |
| DOI |
https://doi.org/10.3748/wjg.119220 |
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