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Articles Published Processes
6/25/2026 8:21:21 AM | Browse: 3 | Download: 0
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Received |
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2026-01-26 06:58 |
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Peer-Review Started |
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2026-01-26 07:03 |
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First Decision by Editorial Office Director |
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2026-02-03 11:09 |
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Return for Revision |
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2026-02-03 11:48 |
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Revised |
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2026-02-15 12:15 |
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Publication Fee Transferred |
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2026-02-21 06:33 |
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Second Decision by Editor |
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2026-03-24 02:52 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-04-01 12:10 |
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Articles in Press |
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2026-04-01 12:10 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-06-17 07:34 |
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Publish the Manuscript Online |
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2026-06-25 08:21 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Tongxie Yaofang enhances the homing efficiency of exogenous bone marrow-derived mesenchymal stem cells to the colonic mucosa and alleviates ulcerative colitis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Shan-Shan Gong, Meng-Lin Li, Liu Liu and Bin Lv |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Basic Public Welfare Research Program of Zhejiang Province |
LQ23H270008 |
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| Corresponding Author |
Bin Lv, PhD, Professor, Department of Gastroenterology, The First Affiliated Hospital of Zhejiang Chinese Medical University, No. 54 Youdian Road, Shangcheng District, Hangzhou 310000, Zhejiang Province, China. lvbin@medmail.com.cn |
| Key Words |
Ulcerative colitis; Tongxie Yaofang; Bone marrow-derived mesenchymal stem cells; Stromal cell-derived factor 1; C-X-C motif chemokine ligand 12; C-X-C chemokine receptor type 4; Inflammatory bowel disease; Intestinal mucosal barrier; Traditional Chinese medicine; Migration |
| Core Tip |
Bone marrow-derived mesenchymal stem cells (BMSCs) are a promising therapy for ulcerative colitis (UC). However, their clinical use is limited by poor homing to the colonic mucosa. Tongxie Yaofang (TXYF) is a traditional Chinese medicine formula. Our findings indicate that TXYF enhances the homing of BMSCs to the colonic mucosa and ameliorates symptoms of UC. This effect appears to involve modulation of the stromal cell-derived factor 1/C-X-C chemokine receptor type 4 axis. These findings suggest that TXYF may serve as an adjunct strategy to improve the efficacy of BMSCs-based therapy for UC. |
| Publish Date |
2026-06-25 08:21 |
| Citation |
Gong SS, Li ML, Liu L, Lv B. Tongxie Yaofang enhances the homing efficiency of exogenous bone marrow-derived mesenchymal stem cells to the colonic mucosa and alleviates ulcerative colitis. World J Stem Cells 2026; 18(6): 119228
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| URL |
https://www.wjgnet.com/1948-0210/full/v18/i6/119228.htm |
| DOI |
https://doi.org/10.4252/wjsc.119228 |
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