| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Outpatient visit frequency in patients with overlapping non-erosive reflux disease and epigastric pain syndrome: A multicenter study
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Mi Lv, Xin Liu, Kai-Yue Huang, Lu-Si Xu, Hui Che, Meng-Xi Yao and Feng-Yun Wang |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
82374434, 82174363 |
| Youth Science Foundation Project of the National Natural Science Foundation of China |
82205104 |
| Excellent Young Scientific and Technological Talent Training Program of the Fundamental Scientific Research Business Expenses of China Academy of Chinese Medical Sciences |
ZZ16-YQ-002 |
|
| Corresponding Author |
Feng-Yun Wang, Adjunct Professor, Chief Physician, Director, Full Professor, MD, Professor, Institute of Digestive Diseases, Xiyuan Hospital of China Academy of Chinese Medical Sciences, No. 1 Xiyuan Playground, Haidian District, Beijing 100091, China. 18810631761@163.com |
| Key Words |
Non-erosive reflux disease; Epigastric pain syndrome; Biopsychosocial model; Outpatient visits frequency; Cross-sectional study |
| Core Tip |
In this first large-scale multicenter study of overlapping non-erosive reflux disease and epigastric pain syndrome in China, frequent healthcare visits were driven not by symptom severity, but by a profile combining chronicity, psychological distress, and complex medication patterns. A striking interaction between proton pump inhibitor and Chinese herbal medicine use identified a high-need subgroup. These findings highlight the importance of an integrated, psychosomatic approach addressing both peripheral and central mechanisms to reduce the healthcare burden in this population. |
| Publish Date |
2026-07-14 09:34 |
| Citation |
Lv M, Liu X, Huang KY, Xu LS, Che H, Yao MX, Wang FY. Outpatient visit frequency in patients with overlapping non-erosive reflux disease and epigastric pain syndrome: A multicenter study. World J Gastroenterol 2026; 32(28): 119326
|
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i28/119326.htm |
| DOI |
https://doi.org/10.3748/wjg.119326 |
