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8/21/2026 3:32:17 AM | Browse: 3 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 119387
Country Brazil
Received
2026-01-26 02:41
Peer-Review Started
2026-01-26 02:41
First Decision by Editorial Office Director
2026-02-09 09:52
Return for Revision
2026-02-09 09:52
Revised
2026-02-22 00:46
Publication Fee Transferred
2026-03-19 23:15
Second Decision by Editor
2026-05-15 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-05-15 04:16
Articles in Press
2026-05-15 04:16
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-07-20 01:14
Publish the Manuscript Online
2026-08-21 03:32
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Surgery
Manuscript Type Meta-Analysis
Article Title Impact of surgical vs medical management on histologic outcomes in Barrett’s esophagus: A meta-analysis
Manuscript Source Unsolicited Manuscript
All Author List Bruna B M Isbert, Dirceu F Valentini Jr, Vinicius J Campos, Luciano P Marcelino, Lorenzo O Dias and Richard R Gurski
ORCID
Author(s) ORCID Number
Bruna B M Isbert http://orcid.org/0000-0002-6069-7503
Dirceu F Valentini Jr http://orcid.org/0000-0002-5567-0429
Vinicius J Campos http://orcid.org/0000-0003-2115-0932
Luciano P Marcelino http://orcid.org/0000-0002-9257-1016
Lorenzo O Dias http://orcid.org/0009-0005-1026-3044
Richard R Gurski http://orcid.org/0000-0002-5731-6765
Funding Agency and Grant Number
Corresponding Author Richard R Gurski, Associate Professor, Chief, Chief Physician, Director, MD, PhD, Service of Digestive Surgery, Hospital de Clínicas de Porto Alegre (HCPA), No. 2350 Ramiro Barcelos Street, Porto Alegre 90035-903, Rio Grande do Sul, Brazil. rgurski@hcpa.edu.br
Key Words Gastroesophageal reflux disease; Esophagus; Barrett’s esophagus; Adenocarcinoma; Fundoplication; Antireflux surgery; Nissen; Proton pump inhibitor
Core Tip Barrett’s esophagus is a premalignant condition for which the optimal strategy to prevent disease progression remains uncertain. This systematic review and meta-analysis directly compared surgical fundoplication with proton pump inhibitor therapy. Fundoplication was associated with higher rates of histologic regression and a reduced risk of progression to high-grade dysplasia or esophageal adenocarcinoma. By focusing exclusively on these two treatment strategies, this study provides clinically meaningful comparative evidence to inform therapeutic decision-making and long-term management in this high-risk population.
Publish Date 2026-08-21 03:32
Citation

Isbert BBM, Valentini Jr DF, Campos VJ, Marcelino LP, Dias LO, Gurski RR. Impact of surgical vs medical management on histologic outcomes in Barrett’s esophagus: A meta-analysis. World J Gastroenterol 2026; 32(35): 119387

URL https://www.wjgnet.com/1007-9327/full/v32/i35/119387.htm
DOI https://doi.org/10.3748/wjg.119387
Full Article (PDF) WJG-32-119387-with-cover.pdf
PRISMA 2009 Checklist 119387-PRISMA-2009-Checklist.pdf
Manuscript File 119387_Auto_Edited_015948.docx
Answering Reviewers 119387-answering-reviewers.pdf
Audio Core Tip 119387-audio.mp3
Biostatistics Review Certificate 119387-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 119387-conflict-of-interest-statement.pdf
Copyright License Agreement 119387-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 119387-non-native-speakers.pdf
Peer-review Report 119387-peer-reviews.pdf
Scientific Misconduct Check 119387-scientific-misconduct-check.png
CrossCheck Report 119387-crosscheck-report.pdf