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Articles Published Processes
5/19/2026 7:13:10 AM | Browse: 0 | Download: 0
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Received |
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2026-01-26 00:40 |
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Peer-Review Started |
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2026-01-26 00:42 |
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First Decision by Editorial Office Director |
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2026-02-28 06:50 |
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Return for Revision |
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2026-02-28 06:50 |
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Revised |
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2026-03-01 15:54 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-04-03 02:42 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-04-03 06:27 |
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Articles in Press |
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2026-04-03 06:27 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-05-13 00:44 |
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Publish the Manuscript Online |
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2026-05-19 07:13 |
| ISSN |
1949-8462 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cardiac & Cardiovascular Systems |
| Manuscript Type |
Opinion Review |
| Article Title |
When the liver hardens the heart: Valvular calcification as an emerging cardiohepatic phenotype in cirrhosis
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Yasser Fouad and Amr Abdel Zaher Shehata |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Yasser Fouad, Department of Gastroenterology and Endemic Medicine, Faculty of Medicine Minia University, Minia university, Minia 19111, Egypt. yasserfouad10@yahoo.com |
| Key Words |
Cirrhosis; Cardiohepatic interaction; Valvular calcification; Metabolic dusfunction; Fatty liver; Risk stratification |
| Core Tip |
One new but little-known aspect of cardiohepatic disease is valve calcification. According to the study by Vuckovic et al, cirrhosis of any aetiology strongly predicts mitral annular calcification, even in the presence of fewer conventional cardiovascular risk factors, whereas fatty liver-related cirrhosis is independently linked to aortic valve calcification. These results imply that a unique pro-calcific cardiovascular phenotype caused by hepatic and metabolic dysfunction is promoted by cirrhosis. Regular evaluation of cirrhosis and transplants should include echocardiographic assessment of valvular calcification to enhance cardiovascular risk stratification and facilitate early, multidisciplinary intervention. |
| Publish Date |
2026-05-19 07:13 |
| Citation |
Fouad Y, Shehata AAZ. When the liver hardens the heart: Valvular calcification as an emerging cardiohepatic phenotype in cirrhosis. World J Cardiol 2026; 18(5): 119394 |
| URL |
https://www.wjgnet.com/1949-8462/full/v18/i5/119394.htm |
| DOI |
https://dx.doi.org/10.4330/wjc.v18.i5.119394 |
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