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Publication Name World Journal of Hepatology
Manuscript ID 119408
Country Saudi Arabia
Received
2026-01-27 05:59
Peer-Review Started
2026-01-27 05:59
First Decision by Editorial Office Director
2026-02-06 10:20
Return for Revision
2026-02-06 10:20
Revised
2026-02-13 11:19
Publication Fee Transferred
2026-02-17 08:56
Second Decision by Editor
2026-03-25 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-03-25 08:30
Articles in Press
2026-03-25 08:30
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-05-14 08:20
Publish the Manuscript Online
2026-05-26 03:52
ISSN 1948-5182 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Systematic Reviews
Article Title Diagnostic and prognostic utility of serum bile acid in liver transplant recipients: A systematic review and quantitative synthesis
Manuscript Source Unsolicited Manuscript
All Author List Eyad Gadour, Hadi Kuriry, Bogdan Miutescu, Bodour Raheem, Syed A Gardezi and Mohammed S AlQahtani
ORCID
Author(s) ORCID Number
Eyad Gadour http://orcid.org/0000-0001-5087-1611
Bogdan Miutescu http://orcid.org/0000-0002-5336-5789
Funding Agency and Grant Number
Corresponding Author Eyad Gadour, CCST, Consultant, FACP, FRCP, MD, MRCP, Professor, Multiorgan Transplant Centre of Excellence, Liver Transplantation Unit, King Fahad Specialist Hospital, Ammar Bin Thabit Street, Dammam 32253, Saudi Arabia. eyadgadour@doctors.org.uk
Key Words Serum bile acid; Liver transplantation; Surveillance strategies; Graft dysfunction; Graft rejection; Biliary complications
Core Tip Serum bile acid (SBA) levels serve as a sensitive, non-invasive biomarker for early detection and prognosis of graft dysfunction, acute rejection, patient survival, and biliary complications following liver transplantation. Elevated SBA levels correlate strongly with adverse outcomes, often preceding changes in conventional liver function tests. Despite promising diagnostic accuracy, heterogeneity in assay methods and cutoff values limits routine clinical use. Standardized protocols and large multicenter prospective studies are needed to validate SBA monitoring as a complementary tool to established biochemical tests, enhancing post-transplant surveillance and timely intervention strategies.
Publish Date 2026-05-26 03:52
Citation

Gadour E, Kuriry H, Miutescu B, Raheem B, Gardezi SA, AlQahtani MS. Diagnostic and prognostic utility of serum bile acid in liver transplant recipients: A systematic review and quantitative synthesis. World J Hepatol 2026; 18(5): 119408

URL https://www.wjgnet.com/1948-5182/full/v18/i5/119408.htm
DOI https://dx.doi.org/10.4254/wjh.v18.i5.119408
Full Article (PDF) WJH-18-119408-with-cover.pdf
PRISMA 2009 Checklist 119408-PRISMA-2009-Checklist.pdf
Manuscript File 119408_Auto_Edited_124725.docx
Answering Reviewers 119408-answering-reviewers.pdf
Audio Core Tip 119408-audio.m4a
Biostatistics Review Certificate 119408-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 119408-conflict-of-interest-statement.pdf
Copyright License Agreement 119408-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 119408-non-native-speakers.pdf
Peer-review Report 119408-peer-reviews.pdf
Scientific Misconduct Check 119408-scientific-misconduct-check.png
Scientific Editor Work List 119408-scientific-editor-work-list.pdf
CrossCheck Report 119408-crosscheck-report.pdf