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Articles Published Processes
9/17/2026 5:48:22 AM | Browse: 0 | Download: 0
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Received |
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2026-01-28 03:10 |
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Peer-Review Started |
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2026-01-28 03:10 |
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First Decision by Editorial Office Director |
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2026-01-30 09:04 |
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Return for Revision |
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2026-01-30 09:04 |
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Revised |
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2026-02-04 08:41 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-03-03 02:36 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-03-03 08:40 |
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Articles in Press |
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2026-03-03 08:40 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-07-15 09:59 |
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Publish the Manuscript Online |
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2026-09-17 05:48 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Correspondence |
| Article Title |
Letter to the Editor: Enhancing fibrosis prediction in metabolic dysfunction-associated steatotic liver disease: The potential of combined biomarker approaches
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Hai-Sheng Hu, Lin-Shu Xu and Bao-Qing Sun |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Bao-Qing Sun, Professor, Department of Clinical Laboratory, The First Affiliated Hospital of Guangzhou Medical University, No. 28 Qiaozhong Middle Road, Guangzhou 510120, Guangdong Province, China. sunbaoqing@vip.163.com |
| Key Words |
Metabolic dysfunction-associated steatotic liver disease; Liver fibrosis; Biomarkers; Diagnostic strategy; Inflammatory indices |
| Core Tip |
This letter highlights the limited diagnostic accuracy of conventional markers (e.g., neutrophil-to-lymphocyte ratio and C-reactive protein) for predicting liver fibrosis in metabolic dysfunction-associated steatotic liver disease. To advance precision management, we propose a shift toward an integrated diagnostic paradigm. This strategy combines accessible systemic inflammation indices with novel biomarkers reflecting specific hepatic processes, such as N-terminal propeptide of type III collagen for fibrogenesis, liver-specific microRNAs, and metabolic proteins, such as fatty acid-binding protein 4. Future research should prioritize validating such mechanism-informed combinations to enable multidimensional risk assessment, establish actionable clinical thresholds, and guide personalized monitoring and intervention, ultimately improving prognosis in this heterogeneous patient population. |
| Publish Date |
2026-09-17 05:48 |
| Citation |
Hu HS, Xu LS, Sun BQ. Letter to the Editor: Enhancing fibrosis prediction in metabolic dysfunction-associated steatotic liver disease: The potential of combined biomarker approaches. World J Hepatol 2026; 18(9): 119430
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| URL |
https://www.wjgnet.com/1948-5182/full/v18/i9/119430.htm |
| DOI |
https://doi.org/10.4254/wjh.119430 |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
