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Articles Published Processes
6/16/2026 8:10:08 AM | Browse: 0 | Download: 0
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Received |
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2026-01-28 03:47 |
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Peer-Review Started |
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2026-01-28 03:48 |
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First Decision by Editorial Office Director |
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2026-02-25 08:30 |
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Return for Revision |
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2026-02-25 08:30 |
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Revised |
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2026-03-29 19:40 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-04-15 02:37 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-04-15 07:47 |
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Articles in Press |
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2026-04-15 07:47 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-04-30 09:27 |
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Publish the Manuscript Online |
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2026-06-16 08:10 |
| ISSN |
2220-315x (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Urology & Nephrology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Forgotten compartment: Impact of tubulointerstitial inflammation and damage on renal outcomes in lupus nephritis from Saudi Arabia
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Muhammad Abdul Mabood Khalil, Nihal Mohammed Sadagah, Hinda Hassan Khideer Mahmood, Fadel Alrowaie, Abdullah Mohammed Almansour, Rayan Mohammed H Alghamdi, Lama Alghamdi, Rawan A Al-Ghamdi, Ammar Elgadi and Salem H Al-Qurashi |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Muhammad Abdul Mabood Khalil, Center of Renal Diseases and Transplantation, King Fahad Armed Forces Hospital, Al Kurnaysh Br Road, Al Andalus, Jeddah 23311, Makkah al Mukarramah, Saudi Arabia. doctorkhalil1975@hotmail.com |
| Key Words |
Lupus nephritis; Tubulointerstitial inflammation; Tubulointerstitial damage; Renal biopsy; Renal outcomes; Prognosis; Saudi Arabia |
| Core Tip |
Although current lupus nephritis (LN) classifications focus mainly on glomerular lesions, tubulointerstitial involvement is frequent and clinically relevant. In this Saudi cohort, the presence of combined tubulointerstitial inflammation and damage was associated with proliferative disease, higher activity and chronicity scores, and poorer renal outcomes. These patients achieved remission more slowly and less often during follow-up. Baseline kidney function, systemic inflammation, and selected histologic features further influenced prognosis. Detailed assessment of the tubulointerstitial compartment may therefore add meaningful prognostic information in LN. |
| Publish Date |
2026-06-16 08:10 |
| Citation |
Khalil MAM, Sadagah NM, Mahmood HHK, Alrowaie F, Almansour AM, Alghamdi RMH, Alghamdi L, A Al-Ghamdi R, Elgadi A, Al-Qurashi SH. Forgotten compartment: Impact of tubulointerstitial inflammation and damage on renal outcomes in lupus nephritis from Saudi Arabia. World J Exp Med 2026; 16(2): 119440
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| URL |
https://www.wjgnet.com/2220-315x/full/v16/i2/119440.htm |
| DOI |
https://doi.org/10.5493/wjem.v16.i2.119440 |
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