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Articles Published Processes
7/14/2026 9:34:57 AM | Browse: 2 | Download: 0
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Received |
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2026-01-28 06:43 |
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Peer-Review Started |
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2026-01-28 06:44 |
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First Decision by Editorial Office Director |
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2026-02-26 07:57 |
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Return for Revision |
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2026-02-26 07:57 |
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Revised |
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2026-03-19 03:13 |
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Publication Fee Transferred |
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2026-03-20 02:39 |
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Second Decision by Editor |
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2026-04-02 02:37 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-04-02 09:02 |
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Articles in Press |
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2026-04-02 09:02 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-06-25 08:29 |
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Publish the Manuscript Online |
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2026-07-14 09:34 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Fibrosis index nine superiority for cirrhosis in hypopituitarism: Clinical validation of endocrine liver triage tool
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ting Li, Xi Wang, Min Nie, Qin Han, Xue-Yan Wu and Jiang-Feng Mao |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Jiang-Feng Mao, MD, Professor, Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 1 Shuaifuyuan, Dongcheng District, Beijing, China, Beijing 100730, China. maojf@pumch.cn |
| Key Words |
Hypopituitarism; Liver fibrosis; Cirrhosis; Non-invasive test; Craniopharyngioma; Fibrosis-9 index; Fibrosis-4 index; Aspartate aminotransferase-to-platelet ratio index; Liver stiffness measurement; Metabolic dysfunction-associated steatotic liver disease |
| Core Tip |
Patients with hypopituitarism are at high risk for rapidly progressive metabolic liver disease, yet traditional non-invasive tests often lack accuracy in this specific endocrine-mediated context. This study provides the first clinical validation of the fibrosis-9 (FIB-9) index in hypopituitary patients. Our findings reveal that FIB-9 (area under the receiver operating characteristic curve = 0.941) significantly outperforms aspartate aminotransferase-to-platelet ratio index, fibrosis-4, and conventional serum markers in identifying cirrhosis. Using an optimal cutoff of 1.748, FIB-9 serves as a highly reliable triage tool, enabling clinicians to accurately identify high-risk patients for advanced liver assessment while sparing others from unnecessary testing. |
| Publish Date |
2026-07-14 09:34 |
| Citation |
Li T, Wang X, Nie M, Han Q, Wu XY, Mao JF. Fibrosis index nine superiority for cirrhosis in hypopituitarism: Clinical validation of endocrine liver triage tool. World J Gastroenterol 2026; 32(28): 119442
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| URL |
https://www.wjgnet.com/1007-9327/full/v32/i28/119442.htm |
| DOI |
https://doi.org/10.3748/wjg.119442 |
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