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7/14/2026 9:34:58 AM | Browse: 1 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 119462
Country Viet Nam
Received
2026-01-28 00:46
Peer-Review Started
2026-01-28 00:46
First Decision by Editorial Office Director
2026-02-14 07:50
Return for Revision
2026-02-14 07:50
Revised
2026-02-15 03:04
Publication Fee Transferred
Second Decision by Editor
2026-04-08 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-04-08 08:04
Articles in Press
2026-04-08 08:04
Edit the Manuscript by Language Editor
2026-04-09 13:54
Typeset the Manuscript
2026-06-22 07:20
Publish the Manuscript Online
2026-07-14 09:34
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Opinion Review
Article Title Biosimilars in inflammatory bowel disease: Beyond evidence, toward trust and implementation
Manuscript Source Invited Manuscript
All Author List Chuong Dinh Nguyen and Luan Minh Dang
ORCID
Author(s) ORCID Number
Chuong Dinh Nguyen http://orcid.org/0000-0002-7703-0932
Luan Minh Dang http://orcid.org/0000-0002-9295-4308
Funding Agency and Grant Number
Corresponding Author Luan Minh Dang, Lecturer, MD, Department of Gastroenterology, University Medical Center, No. 215 Hong Bang Street, Cho Lon Ward, Ho Chi Minh City 700000, Viet Nam. luan.dm@umc.edu.vn
Key Words Biosimilars; Inflammatory bowel disease; Nocebo effect; Biologic switching; Health equity
Core Tip Biosimilars in inflammatory bowel disease have moved beyond a narrow question of pharmacological equivalence. Although current evidence supports their efficacy, safety, and use across multiple clinical scenarios, adoption remains limited by nocebo-related discontinuation, physician hesitation, and system-level implementation barriers. This opinion review synthesizes current evidence, examines persistent controversies, and proposes a pragmatic 5-step framework for biosimilar initiation or switching in routine care. It also highlights the special challenges of resource-limited settings and introduces the concept of a “nocebo-prone environment” as a practical lens for understanding barriers to equitable biosimilar integration.
Publish Date 2026-07-14 09:34
Citation

Nguyen CD, Dang LM. Biosimilars in inflammatory bowel disease: Beyond evidence, toward trust and implementation. World J Gastroenterol 2026; 32(28): 119462

URL https://www.wjgnet.com/1007-9327/full/v32/i28/119462.htm
DOI https://doi.org/10.3748/wjg.119462
Full Article (PDF) WJG-32-119462-with-cover.pdf
Manuscript File 119462_Auto_Edited_132001.docx
Answering Reviewers 119462-answering-reviewers.pdf
Audio Core Tip 119462-audio.m4a
Conflict-of-Interest Disclosure Form 119462-conflict-of-interest-statement.pdf
Copyright License Agreement 119462-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 119462-non-native-speakers.pdf
Peer-review Report 119462-peer-reviews.pdf
Scientific Misconduct Check 119462-scientific-misconduct-check.png
Scientific Editor Work List 119462-scientific-editor-work-list.pdf
CrossCheck Report 119462-crosscheck-report.pdf