Publication Name	World Journal of Gastroenterology
Manuscript ID	11947
Country	United States

Received	2014-06-13 08:01
Peer-Review Started	2014-06-13 18:01
To Make the First Decision	2014-06-27 17:38
Return for Revision	2014-07-07 13:47
Revised	2014-07-20 00:00
Second Decision	2014-11-27 21:22
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-12-01 13:27
Articles in Press	2014-12-01 13:58
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-12-11 16:01
Publish the Manuscript Online	2014-12-20 19:42

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Per-oral endoscopic myotomy: Major advance in achalasia treatment and in endoscopic surgery
Manuscript Source	Invited Manuscript
All Author List	David Friedel, Rani Modayil and Stavros N Stavropoulos
Funding Agency and Grant Number
Corresponding Author	Stavros N Stavropoulos, MD, Director of Endoscopy, Department of Gastroenterology, Hepatology and Nutrition, Winthrop University Hospital, 222 Station Plaza North Suite 429, Mineola, NY 11501, United States. sstavropoulos@winthrop.org
Key Words	Per oral endoscopic myotomy; Achalasia; Natural orifice transluminal endoscopic surgery; Submucosal tunnel endoscopic resection; Submucosal tunnel endoscopy; Endoscopic suturing; Endoscopic myotomy; Endoscopic submucosal dissection; EndoFLIP
Core Tip	Per-oral endoscopic myotomy (POEM) is a novel endosurgical therapy for achalasia. POEM developed as an offshoot of early natural orifice endoscopic surgery (NOTES) approach investigation, but, now, is arguably the most successful clinical application of NOTES. The clinical results of POEM therapy in terms of dysphagia relief and safety have been excellent. The impact of POEM is extending far beyond the narrow domain of esophageal motility disorders. As the first successful clinical application of submucosal endoscopy it is now spawning many other NOTES interventions utilizing a submucosal tunnel approach including submucosal tunnel endoscopic resection of submucosal and mucosal lesions and per oral pyloromyotomy for gastroparesis.
Publish Date	2014-12-20 19:42
Citation	Friedel D, Modayil R, Stavropoulos SN. Per-oral endoscopic myotomy: Major advance in achalasia treatment and in endoscopic surgery. World J Gastroenterol 2014; 20(47): 17746-17755
URL	http://www.wjgnet.com/1007-9327/full/v20/i47/17746.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i47.17746

Full Article (PDF)	WJG-20-17746.pdf
Full Article (Word)	WJG-20-17746.doc
Manuscript File	11947-Review.doc
Answering Reviewers	11947-Answering reviewers.pdf
Copyright License Agreement	11947-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	Ethics_Committee_20140613050145.pdf
Peer-review Report	11947-Peer reviews.pdf
Scientific Misconduct Check	11947-CrossCheck.jpg
Scientific Editor Work List	11947-Scientific editor work list.pdf