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Articles Published Processes
10/9/2026 8:15:19 AM | Browse: 3 | Download: 2
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Received |
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2026-01-28 03:12 |
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Peer-Review Started |
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2026-01-28 03:20 |
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First Decision by Editorial Office Director |
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2026-02-10 09:02 |
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Return for Revision |
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2026-02-10 09:02 |
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Revised |
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2026-02-18 06:58 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-05-14 02:44 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-05-14 08:26 |
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Articles in Press |
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2026-05-14 08:26 |
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Edit the Manuscript by Language Editor |
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2026-05-18 16:35 |
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Typeset the Manuscript |
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2026-09-08 08:17 |
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Publish the Manuscript Online |
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2026-10-09 08:15 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell & Tissue Engineering |
| Manuscript Type |
Opinion Review |
| Article Title |
Integrin-driven differences in extracellular matrix regulation of 3D-cultured tumor cells
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ilya Klabukov, Daria Eygel and Denis S Baranovskii |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ilya Klabukov, Associate Professor, Head, PhD, Department of Regenerative Medicine, National Medical Research Radiological Center, 4 Koroleva Street, Obninsk 249036, Kaluzhskaya Oblast’, Russia. ilya.klabukov@gmail.com |
| Key Words |
Cancer; Cell regulation; Epithelial-mesenchymal transition; Extracellular matrix; Integrins; Spheroids; Tumor microenvironment |
| Core Tip |
Differences in gene regulation between 3D-cultured mesenchymal and epithelial cells extend beyond the epithelial-mesenchymal transition and influence how tumor cells interact with a newly synthesized extracellular matrix. Regulation of integrin density and spatial distribution appears to play a central role in mediating cell-extracellular matrix interactions and may explain the distinct behaviors observed in tumor tissue models between different cell responses. |
| Publish Date |
2026-10-09 08:15 |
| Citation |
Klabukov I, Eygel D, Baranovskii DS. Integrin-driven differences in extracellular matrix regulation of 3D-cultured tumor cells. World J Gastrointest Oncol 2026; 18(10): 119474
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| URL |
https://www.wjgnet.com/1948-5204/full/v18/i10/119474.htm |
| DOI |
https://doi.org/10.4251/wjgo.119474 |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
