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Articles Published Processes
6/24/2026 9:13:59 AM | Browse: 1 | Download: 0
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Received |
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2026-01-29 02:56 |
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Peer-Review Started |
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2026-01-29 02:57 |
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First Decision by Editorial Office Director |
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2026-02-14 07:25 |
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Return for Revision |
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2026-02-14 07:25 |
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Revised |
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2026-03-04 11:53 |
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Publication Fee Transferred |
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2026-03-08 13:33 |
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Second Decision by Editor |
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2026-03-25 02:38 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-03-25 06:08 |
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Articles in Press |
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2026-03-25 06:08 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-05-27 00:31 |
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Publish the Manuscript Online |
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2026-06-24 09:13 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Anesthesiology |
| Manuscript Type |
Clinical Trials Study |
| Article Title |
Effects of esketamine on perioperative renal injury in paediatric patients undergoing living donor liver transplantation
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hong-Xia Li, Gui-Zhu Cao, Yi-Qi Weng, Ai-Li Dong, Wei Gao, Min Zhu, Lu Che and Wen-Li Yu |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Research Fund for Liquid Therapy in Anesthesiology Medicine |
YLGX-MZ-2022008 |
| the Tianjin Key Clinical Speciality (Anaesthesiology) Construction Project |
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| the Tianjin Key Medical Construction Project |
TJYXZDXK-3-022C |
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| Corresponding Author |
Wen-Li Yu, Department of Anaesthesiology, Tianjin First Central Hospital, No. 24, Fukang Road, Nankai District, Tianjin 300192, Nankai District, China. 5020201005@nankai.edu.cn |
| Key Words |
Esketamine; Paediatric living-donor liver transplantation; Acute kidney injury; Ischaemia-reperfusion injury; Renal protection; Inflammatory factors; Paediatric anaesthesia |
| Core Tip |
This randomized controlled trial demonstrates that, compared with the control group, intraoperative esketamine administration significantly attenuates the increase in serum creatinine levels following ischemia-reperfusion injury and attenuates the systemic inflammatory response in pediatric patients undergoing living donor liver transplantation. The renoprotective effects are mediated by the suppression of tumour necrosis factor-α, interleukin-18, and neutrophil gelatinase-associated lipocalin, alongside hemodynamic stabilization. Esketamine may be considered as a component of anesthetic management to mitigate perioperative renal injury in this high-risk population. |
| Publish Date |
2026-06-24 09:13 |
| Citation |
Li HX, Cao GZ, Weng YQ, Dong AL, Gao W, Zhu M, Che L, Yu WL. Effects of esketamine on perioperative renal injury in paediatric patients undergoing living donor liver transplantation. World J Gastrointest Surg 2026; 18(6): 119494
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| URL |
https://www.wjgnet.com/1948-9366/full/v18/i6/119494.htm |
| DOI |
https://doi.org/10.4240/wjgs.119494 |
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