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Publication Name World Journal of Transplantation
Manuscript ID 119505
Country United States
Received
2026-02-06 00:37
Peer-Review Started
2026-02-06 00:44
First Decision by Editorial Office Director
2026-02-25 08:06
Return for Revision
2026-02-25 08:06
Revised
2026-04-01 15:34
Publication Fee Transferred
Second Decision by Editor
2026-06-05 03:10
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-06-05 06:39
Articles in Press
2026-06-05 06:39
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-07-29 10:02
Publish the Manuscript Online
2026-09-02 06:21
ISSN 2220-3230 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Transplantation
Manuscript Type Retrospective Cohort Study
Article Title Higher model for end-stage liver disease excluding international normalized ratio scores predict worse kidney graft outcomes in simultaneous heart-kidney transplantation
Manuscript Source Invited Manuscript
All Author List Marco E Diaz-Cordova, Matthew Rega, Ishani Sharma, Ryosuke Misawa, Abhay Dhand, Seigo Nishida and Kenji Okumura
ORCID
Author(s) ORCID Number
Ryosuke Misawa http://orcid.org/0000-0001-8429-3135
Abhay Dhand http://orcid.org/0000-0003-3527-1938
Seigo Nishida http://orcid.org/0000-0002-1504-3551
Kenji Okumura http://orcid.org/0000-0002-7751-2624
Funding Agency and Grant Number
Corresponding Author Kenji Okumura, Associate Faculty, MD, Department of Surgery, Westchester Medical Center and New York Medical College, 100 Woods Road, Valhalla, NY 10595, United States. kenji.okumura@wmchealth.org
Key Words Simultaneous heart-kidney transplant; Model for end-stage liver disease excluding international normalized ratio; Heart transplant; Kidney transplant; Predictor; Transplant outcomes; Delayed graft dysfunction
Core Tip The incidence of simultaneous heart-kidney transplantation (SHKT) has increased substantially in recent years. Early studies suggested benefit, but recent data are conflicting. No reliable prognostic marker exists for this population. The model for end-stage liver disease excluding international normalized ratio (MELD-XI) was previously validated in heart transplantation and cardiac surgery and may serve as a risk-stratification tool. In this study, higher MELD-XI scores were linked to early mortality and kidney graft failure. This supports its potential role in guiding selection between SHKT and kidney-after-heart transplantation under current allocation policies.
Publish Date 2026-09-02 06:21
Citation

Diaz-Cordova ME, Rega M, Sharma I, Misawa R, Dhand A, Nishida S, Okumura K. Higher model for end-stage liver disease excluding international normalized ratio scores predict worse kidney graft outcomes in simultaneous heart-kidney transplantation. World J Transplant 2026; 16(3): 119505

URL https://www.wjgnet.com/2220-3230/full/v16/i3/119505.htm
DOI https://doi.org/10.5500/wjt.119505
Full Article (PDF) WJT-16-119505-with-cover.pdf
STROBE Statement 119505-STROBE-statement.pdf
Manuscript File 119505_Auto_Edited_032825.docx
Answering Reviewers 119505-answering-reviewers.pdf
Audio Core Tip 119505-audio.m4a
Biostatistics Review Certificate 119505-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 119505-conflict-of-interest-statement.pdf
Copyright License Agreement 119505-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 119505-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 119505-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 119505-non-native-speakers.pdf
Supplementary Material 119505-supplementary-material.pdf
Peer-review Report 119505-peer-reviews.pdf
Scientific Misconduct Check 119505-scientific-misconduct-check.png
CrossCheck Report 119505-crosscheck-report.pdf