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5/19/2026 7:13:09 AM | Browse: 0 | Download: 0
Publication Name World Journal of Cardiology
Manuscript ID 119513
Country Indonesia
Received
2026-01-30 00:25
Peer-Review Started
2026-01-30 00:31
First Decision by Editorial Office Director
2026-02-02 08:58
Return for Revision
2026-02-02 08:58
Revised
2026-02-04 15:23
Publication Fee Transferred
Second Decision by Editor
2026-03-10 02:47
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-03-10 11:06
Articles in Press
2026-03-10 11:06
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-05-13 00:49
Publish the Manuscript Online
2026-05-19 07:13
ISSN 1949-8462 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cardiac & Cardiovascular Systems
Manuscript Type Opinion Review
Article Title Significance of flow mediated dilation in evaluating endothelial dysfunction in vasospastic angina
Manuscript Source Invited Manuscript
All Author List Wilbert Huang
ORCID
Author(s) ORCID Number
Wilbert Huang http://orcid.org/0000-0003-4637-0819
Funding Agency and Grant Number
Corresponding Author Wilbert Huang, MD, Senior Research Fellow, Faculty of Medicine, University of Padjadjaran, Jl. Dipatiukur No. 35, Bandung 40416, West Java, Indonesia. wilberthuang67@gmail.com
Key Words Flow mediated dilation; Vasospastic angina; Endothelial dysfunction; Coronary artery disease; Prognosis
Core Tip  This study emphasizes the prognostic importance of endothelial-dependent vasodilation assessed by flow-mediated dilation (FMD) in patients with vasospastic angina. Unlike nitroglycerin-induced dilation, FMD was independently associated with major adverse cardiovascular events, underscoring the pivotal role of endothelial dysfunction rather than vascular smooth muscle impairment. Careful model construction avoided overfitting despite limited events. Given its non-invasive nature, FMD may serve as a valuable risk-stratification and potentially diagnostic tool in vasospastic angina, warranting further prospective validation.
Publish Date 2026-05-19 07:13
Citation

Huang W. Significance of flow mediated dilation in evaluating endothelial dysfunction in vasospastic angina. World J Cardiol 2026; 18(5): 119513

URL https://www.wjgnet.com/1949-8462/full/v18/i5/119513.htm
DOI https://dx.doi.org/10.4330/wjc.v18.i5.119513
Full Article (PDF) WJC-18-119513-with-cover.pdf
Manuscript File 119513_Auto_Edited_013029.docx
Answering Reviewers 119513-answering-reviewers.pdf
Audio Core Tip 119513-audio.mp3
Conflict-of-Interest Disclosure Form 119513-conflict-of-interest-statement.pdf
Copyright License Agreement 119513-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 119513-non-native-speakers.pdf
Peer-review Report 119513-peer-reviews.pdf
Scientific Misconduct Check 119513-scientific-misconduct-check.png
Scientific Editor Work List 119513-scientific-editor-work-list.pdf
CrossCheck Report 119513-crosscheck-report.pdf