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Articles Published Processes
8/25/2026 6:38:37 AM | Browse: 3 | Download: 0
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Received |
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2026-01-30 01:00 |
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Peer-Review Started |
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2026-01-30 06:57 |
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First Decision by Editorial Office Director |
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2026-02-26 08:17 |
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Return for Revision |
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2026-02-26 08:17 |
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Revised |
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2026-04-19 02:53 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-05-14 02:46 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-05-14 06:25 |
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Articles in Press |
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2026-05-14 06:25 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-08-14 00:24 |
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Publish the Manuscript Online |
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2026-08-25 06:38 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Clinical Neurology |
| Manuscript Type |
Opinion Review |
| Article Title |
Gut microbiota-multi-organ axis and neuroinflammatory network: A potential integrative hub in aging and age-related diseases
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Zi-Wei Hou, Pan Zhang and Chen Chen |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Shanxi Province Chinese Medicine Science and Technology Special Research Project |
No. 2024ZYY2A023 |
| Integration of Medicine, Engineering, and Basic Medical Sciences Special Project of Shanxi Provincial Health Commission |
No. 2025YGYL026 |
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| Corresponding Author |
Chen Chen, Department of Neurology, Affiliated Cardiovascular Hospital of Shanxi Medical University, No. 18 Yifen Street, Taiyuan 030024, Shanxi Province, China. chen.chen@sxmu.edu.cn |
| Key Words |
Gut microbiota; Aging; Gut-liver axis; Gut-brain axis; Neuroinflammation; Multi-organ axis; Traditional Chinese medicine |
| Core Tip |
Recent studies have observed functional remodeling of gut microbiota during aging, particularly enhanced lipid metabolism pathways. This article discusses the gut-liver axis and gut-brain axis as potential bridges linking microbial alterations to host aging, with neuroinflammation potentially acting as an integrative hub. Targeting the “microbiota-multi-organ axis-neuroinflammation” network may provide potential directions for future research on healthy aging. |
| Publish Date |
2026-08-25 06:38 |
| Citation |
Hou ZW, Zhang P, Chen C. Gut microbiota-multi-organ axis and neuroinflammatory network: A potential integrative hub in aging and age-related diseases. World J Gastroenterol 2026; 32(36): 119520
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| URL |
https://www.wjgnet.com/1007-9327/full/v32/i36/119520.htm |
| DOI |
https://doi.org/10.3748/wjg.119520 |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
