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Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 119538
Country China
Received
2026-02-02 03:25
Peer-Review Started
2026-02-02 03:26
First Decision by Editorial Office Director
2026-02-27 06:53
Return for Revision
2026-02-27 06:53
Revised
2026-03-11 13:35
Publication Fee Transferred
2026-03-17 15:21
Second Decision by Editor
2026-04-01 02:44
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-04-01 08:28
Articles in Press
2026-04-01 08:28
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-06-09 00:26
Publish the Manuscript Online
2026-06-24 09:13
ISSN 1948-9366 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Randomized Controlled Trial
Article Title Efficacy of linaclotide with polyethylene glycol at high risk of inadequate bowel preparation: A randomized controlled trial
Manuscript Source Unsolicited Manuscript
All Author List Wei-Min Li, Xiao-Peng Wang, Yu-Xuan Li, Yi-Dong Wang, Yi-Jie Sun, Guo-Dong Li and Jia-Qi Wu
ORCID
Author(s) ORCID Number
Wei-Min Li http://orcid.org/0000-0002-4012-5882
Guo-Dong Li http://orcid.org/0000-0003-0800-8640
Jia-Qi Wu http://orcid.org/0009-0008-2694-8429
Funding Agency and Grant Number
Funding Agency Grant Number
Hangzhou Biomedical and Health Industry Development Support Technology Special Project No. 2023WJC080
Hangzhou Medical and Health Science and Technology Project No. A20251519
Corresponding Author Jia-Qi Wu, MD, Department of Gastroenterology, The Affiliated Hospital of Hangzhou Normal University, No. 126 Wenzhou Road, Hangzhou 310000, Zhejiang Province, China. wujiaqi_12@126.com
Key Words Linaclotide; Bowel preparation; High-risk patients; Boston bowel preparation scale; Adequate preparation rate
Core Tip This randomized controlled trial evaluated the efficacy of 3 L polyethylene glycol combined with linaclotide in patients at high risk of inadequate bowel preparation. Linaclotide significantly improved bowel cleansing and the adequacy of bowel preparation. No differences were observed between the groups in adenoma detection rate, polyp detection rate, polyp characteristics, or adverse events. This novel evidence supports the use of 3 L polyethylene glycol with linaclotide for bowel cleansing in high-risk populations.
Publish Date 2026-06-24 09:13
Citation

Li WM, Wang XP, Li YX, Wang YD, Sun YJ, Li GD, Wu JQ. Efficacy of linaclotide with polyethylene glycol at high risk of inadequate bowel preparation: A randomized controlled trial. World J Gastrointest Surg 2026; 18(6): 119538

URL https://www.wjgnet.com/1948-9366/full/v18/i6/119538.htm
DOI https://doi.org/10.4240/wjgs.119538
Full Article (PDF) WJGS-18-119538-with-cover.pdf
CONSORT 2010 Statement 119538-CONSORT-2010-statement.pdf
Manuscript File 119538_Auto_Edited_091618.docx
Answering Reviewers 119538-answering-reviewers.pdf
Audio Core Tip 119538-audio.mp3
Biostatistics Review Certificate 119538-biostatistics-statement.pdf
Clinical Trial Registration Statement 119538-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form 119538-conflict-of-interest-statement.pdf
Copyright License Agreement 119538-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 119538-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 119538-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 119538-non-native-speakers.pdf
Peer-review Report 119538-peer-reviews.pdf
Scientific Misconduct Check 119538-scientific-misconduct-check.png
Scientific Editor Work List 119538-scientific-editor-work-list.pdf
CrossCheck Report 119538-crosscheck-report.pdf