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Articles Published Processes
7/14/2026 7:34:00 AM | Browse: 2 | Download: 0
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Received |
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2026-01-30 00:48 |
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Peer-Review Started |
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2026-01-30 00:55 |
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First Decision by Editorial Office Director |
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2026-02-10 10:52 |
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Return for Revision |
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2026-02-10 10:52 |
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Revised |
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2026-02-13 01:37 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-03-10 02:43 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-03-10 10:26 |
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Articles in Press |
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2026-03-10 10:26 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-06-26 04:01 |
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Publish the Manuscript Online |
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2026-07-14 07:34 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Correspondence |
| Article Title |
Letter to the Editor: Trimetazidine modulates gut microbiota-lipid metabolism axis: A novel avenue for anti-aging interventions
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Hai-Bo Wu, Ting Chen and Yi Tian |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Yi Tian, MD, Department of Clinical Medical, Sichuan Provincial People’s Hospital East Sichuan Hospital & Dazhou First People’s Hospital, No. 522 Xiwaita Stone Road, Tongchuan District, Dazhou 635000, Sichuan Province, China. doc.yitian@hotmail.com |
| Key Words |
Gut microbiome; Aging; Trimetazidine; Microbial balance; Metabolism; Senescence; Predictive model |
| Core Tip |
In this letter, we discuss a study by Wang et al on the age-related gut microbiome profile and reversal of microbial imbalance using trimetazidine therapy. This study provided compelling evidence that the gut microbiota undergoes significant age-dependent changes, particularly an enrichment of fatty acid oxidation-related microbes in older populations. The authors successfully demonstrated that trimetazidine restored the gut microbial balance and reduced senescence markers in ageing rats, indicating that it exerts potential anti-ageing effects by modulating the microbiota and metabolism. |
| Publish Date |
2026-07-14 07:34 |
| Citation |
Wu HB, Chen T, Tian Y. Letter to the Editor: Trimetazidine modulates gut microbiota-lipid metabolism axis: A novel avenue for anti-aging interventions. World J Gastroenterol 2026; 32(27): 119545
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| URL |
https://www.wjgnet.com/1007-9327/full/v32/i27/119545.htm |
| DOI |
https://doi.org/10.3748/wjg.119545 |
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