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Articles Published Processes
6/25/2026 8:21:23 AM | Browse: 0 | Download: 0
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Received |
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2026-03-25 10:19 |
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Peer-Review Started |
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2026-03-25 10:19 |
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First Decision by Editorial Office Director |
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2026-04-10 07:52 |
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Return for Revision |
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2026-04-10 07:52 |
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Revised |
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2026-04-24 11:31 |
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Publication Fee Transferred |
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2026-04-28 02:39 |
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Second Decision by Editor |
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2026-05-20 02:43 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-05-27 08:03 |
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Articles in Press |
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2026-05-27 08:03 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-06-15 06:08 |
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Publish the Manuscript Online |
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2026-06-25 08:21 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Cancer stem cell-associated markers and their prognostic value in non-small cell lung cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Lin-Lin Luo, Si-Cong Jiang, Shuo Li, Guang-Yi Zhang, Jian-Jun Tang and You-Dan Guo |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
You-Dan Guo, MD, Department of Respiratory Disease, Jiangxi Provincial People’s Hospital, No. 92 Aiguo Road, Nanchang 330006, Jiangxi Province, China. 13970945069@163.com |
| Key Words |
Non-small cell lung cancer; Cancer stem cells; CD133; Aldehyde dehydrogenase 1A1; SRY-box transcription factor 2; Prognosis |
| Core Tip |
Cancer stem cells (CSCs) are key drivers of tumor recurrence, metastasis, and therapeutic resistance in non-small cell lung cancer. This retrospective study systematically evaluated the prognostic significance of the CSC-related markers CD133, aldehyde dehydrogenase 1A1, and SRY-box transcription factor 2 using immunohistochemistry in surgically resected non-small cell lung cancer tissues. We further developed a composite CSC score integrating multiple stemness markers, which significantly improved the prognostic stratification beyond conventional clinicopathological factors. Its potential clinical value lies in complementary postoperative risk enrichment, closer surveillance planning, and future integration with molecular subtyping, rather than the replacement of existing decision frameworks. |
| Publish Date |
2026-06-25 08:21 |
| Citation |
Luo LL, Jiang SC, Li S, Zhang GY, Tang JJ, Guo YD. Cancer stem cell-associated markers and their prognostic value in non-small cell lung cancer. World J Stem Cells 2026; 18(6): 119550
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| URL |
https://www.wjgnet.com/1948-0210/full/v18/i6/119550.htm |
| DOI |
https://doi.org/10.4252/wjsc.119550 |
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