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Publication Name World Journal of Clinical Cases
Manuscript ID 119557
Country Pakistan
Received
2026-02-02 01:14
Peer-Review Started
2026-02-02 01:14
First Decision by Editorial Office Director
2026-02-27 08:49
Return for Revision
2026-02-27 08:49
Revised
2026-03-08 18:53
Publication Fee Transferred
Second Decision by Editor
2026-04-09 02:32
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-04-09 03:54
Articles in Press
2026-04-09 03:54
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-04-29 06:13
Publish the Manuscript Online
2026-06-03 07:29
ISSN 2307-8960 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Orthopedics
Manuscript Type Retrospective Cohort Study
Article Title Bone morphogenetic protein alone vs in combination with bone graft in management of non-union of tibia fractures
Manuscript Source Invited Manuscript
All Author List Raja Muhammad Mussab, Sharjeel Khan, Hadia Javed, Shehanshah Muhammad Arqam, Shehzadi Rimsha and Safeer Ahmad Javaid
ORCID
Author(s) ORCID Number
Raja Muhammad Mussab http://orcid.org/0009-0008-0864-2821
Funding Agency and Grant Number
Corresponding Author Raja Muhammad Mussab, T&O, Orthopaedics and Trauma, Jinnah Postgraduate Medical Centre, Karachi, PA, Raja Muhammad Mussab <email>mussabafaq@hotmail.com</email>, Karachi 75510, Sindh, Pakistan. mussabafaq@hotmail.com
Key Words Tibia; Non unions; Bone morphogenetic protein; Bone grafts; Fractures; Healing; Fractures
Core Tip Non-union of tibial fractures remains a significant challenge in orthopaedic trauma practice, often associated with prolonged morbidity and a substantial economic burden on healthcare systems. Bone morphogenetic proteins (BMPs) have emerged as a promising biological agent in fracture healing; however, their use in clinical practice, either alone or in combination with bone grafting techniques, remains variable and sometimes controversial due to cost-effectiveness and clinical outcomes. Our study directly compares the outcomes of BMP use alone vs in combination with autologous bone grafts in managing tibial non-unions. This manuscript contributes provides valuable insights that can aid clinical decision-making, particularly in resource-limited settings where the optimal use of biologics must be balanced against surgical and economic factors.
Publish Date 2026-06-03 07:29
Citation

Mussab RM, Khan S, Javed H, Arqam SM, Rimsha S, Javaid SA. Bone morphogenetic protein alone vs in combination with bone graft in management of non-union of tibia fractures. World J Clin Cases 2026; 14(17): 119557

URL https://www.wjgnet.com/2307-8960/full/v14/i17/119557.htm
DOI https://doi.org/10.12998/wjcc.v14.i17.119557
Full Article (PDF) WJCC-14-119557-with-cover.pdf
STROBE Statement 119557-STROBE-statement.pdf
Manuscript File 119557_Auto_Edited_071451.docx
Answering Reviewers 119557-answering-reviewers.pdf
Audio Core Tip 119557-audio.m4a
Biostatistics Review Certificate 119557-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 119557-conflict-of-interest-statement.pdf
Copyright License Agreement 119557-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 119557-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 119557-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 119557-non-native-speakers.pdf
Peer-review Report 119557-peer-reviews.pdf
Scientific Misconduct Check 119557-scientific-misconduct-check.png
Scientific Editor Work List 119557-scientific-editor-work-list.pdf
CrossCheck Report 119557-crosscheck-report.pdf