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8/19/2026 1:55:06 AM | Browse: 1 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 119567
Country China
Received
2026-03-03 10:28
Peer-Review Started
2026-03-03 10:28
First Decision by Editorial Office Director
2026-03-13 09:11
Return for Revision
2026-03-13 09:11
Revised
2026-03-25 03:53
Publication Fee Transferred
2026-03-31 01:26
Second Decision by Editor
2026-05-11 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-05-11 08:06
Articles in Press
2026-05-11 08:06
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-05-31 14:55
Publish the Manuscript Online
2026-08-19 01:55
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Retrospective Study
Article Title Prognostic value of systemic immune-inflammation index in patients with gastric cancer treated with immune checkpoint inhibitors
Manuscript Source Unsolicited Manuscript
All Author List Rui Guo and Meng Gao
ORCID
Author(s) ORCID Number
Rui Guo http://orcid.org/0009-0004-0475-3410
Funding Agency and Grant Number
Corresponding Author Rui Guo, Department of Laboratory Medicine, Henan Provincial People’s Hospital, People’s Hospital of Zhengzhou University, No. 7 Weiwu Road, Jinshui District, Zhengzhou 462000, Henan Province, China. guorui2460@163.com
Key Words Systemic immune-inflammation index; Gastric cancer; Immune checkpoint inhibitors; Prognosis; Biomarkers; Retrospective studies
Core Tip The systemic immune-inflammation index (SII), calculated from routine blood counts, integrates neutrophils, lymphocytes, and platelets to reflect the host immune-inflammatory balance. This retrospective study of 238 advanced gastric cancer patients treated with immune checkpoint inhibitors demonstrates that a high baseline SII (≥ 593.995) independently predicts poor progression-free survival and lower disease control rates. Combining SII with clinical parameters significantly improves predictive accuracy for early progressive disease, suggesting SII as a practical and accessible biomarker for risk stratification in immune checkpoint inhibitors-treated gastric cancer.
Publish Date 2026-08-19 01:55
Citation

Guo R, Gao M. Prognostic value of systemic immune-inflammation index in patients with gastric cancer treated with immune checkpoint inhibitors. World J Gastroenterol 2026; 32(34): 119567

URL https://www.wjgnet.com/1007-9327/full/v32/i34/119567.htm
DOI https://doi.org/10.3748/wjg.v32.i34.119567
Full Article (PDF) WJG-32-119567-with-cover.pdf
Manuscript File 119567_Auto_Edited_010350.docx
Answering Reviewers 119567-answering-reviewers.pdf
Audio Core Tip 119567-audio.mp3
Biostatistics Review Certificate 119567-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 119567-conflict-of-interest-statement.pdf
Copyright License Agreement 119567-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 119567-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 119567-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 119567-non-native-speakers.pdf
Peer-review Report 119567-peer-reviews.pdf
Scientific Misconduct Check 119567-scientific-misconduct-check.png
Scientific Editor Work List 119567-scientific-editor-work-list.pdf
CrossCheck Report 119567-crosscheck-report.pdf