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9/18/2026 3:45:44 AM | Browse: 1 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 119599
Country Italy
Received
2026-02-14 02:29
Peer-Review Started
2026-02-14 02:30
First Decision by Editorial Office Director
2026-02-28 09:31
Return for Revision
2026-02-28 09:31
Revised
2026-03-01 14:59
Publication Fee Transferred
Second Decision by Editor
2026-06-22 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-06-22 06:36
Articles in Press
2026-06-22 06:36
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-07-01 02:45
Publish the Manuscript Online
2026-09-18 03:45
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Opinion Review
Article Title Habitat imaging before transarterial chemoembolization in hepatocellular carcinoma: ready for clinical decision-making?
Manuscript Source Invited Manuscript
All Author List Luca Toti, Renato Argirò and Roberta Angelico
ORCID
Author(s) ORCID Number
Luca Toti http://orcid.org/0000-0001-8407-5939
Renato Argirò http://orcid.org/0000-0002-2878-4658
Roberta Angelico http://orcid.org/0000-0002-3439-7750
Funding Agency and Grant Number
Corresponding Author Luca Toti, Assistant Professor, MD, PhD, HPB and Transplant Unit, Department of Surgical Sciences, University of Rome Tor Vergata, Viale Oxford, 81, Rome 00133, Italy. toti@med.uniroma2.it
Key Words Hepatocellular carcinoma; Transarterial chemoembolization; Magnetic resonance imaging; Habitat imaging; Intratumoral heterogeneity; Precision medicine
Core Tip Habitat imaging offers a different way of reading magnetic resonance imaging in hepatocellular carcinoma, moving beyond simple lesion description and trying to capture the tumor’s internal spatial heterogeneity. Its value lies not only in the possibility of predicting response after transarterial chemoembolization, but also in helping clinicians think more carefully about pretreatment selection and multidisciplinary treatment planning. At present, however, this approach is still constrained by important limitations, including methodological fragility, poor standardization, and the lack of solid prospective validation. The key issue is no longer whether habitat imaging is conceptually attractive, but whether it is robust enough to become genuinely useful in clinical practice.
Publish Date 2026-09-18 03:45
Citation

Toti L, Argirò R, Angelico R. Habitat imaging before transarterial chemoembolization in hepatocellular carcinoma: ready for clinical decision-making? World J Gastroenterol 2026; 32(41): 119599

URL https://www.wjgnet.com/1007-9327/full/v32/i41/119599.htm
DOI https://doi.org/10.3748/wjg.119599
Full Article (PDF) WJG-32-119599-with-cover.pdf
Manuscript File 119599_Auto_Edited_011644.docx
Answering Reviewers 119599-answering-reviewers.pdf
Audio Core Tip 119599-audio.m4a
Conflict-of-Interest Disclosure Form 119599-conflict-of-interest-statement.pdf
Copyright License Agreement 119599-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 119599-non-native-speakers.pdf
Peer-review Report 119599-peer-reviews.pdf
Scientific Misconduct Check 119599-scientific-misconduct-check.png
CrossCheck Report 119599-crosscheck-report.pdf