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6/25/2026 6:40:07 AM | Browse: 0 | Download: 0
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Received |
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2026-02-02 00:51 |
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Peer-Review Started |
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2026-02-02 00:52 |
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First Decision by Editorial Office Director |
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2026-02-12 08:25 |
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Return for Revision |
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2026-02-12 08:25 |
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Revised |
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2026-02-20 00:33 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-03-24 02:48 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-03-24 07:50 |
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Articles in Press |
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2026-03-24 07:50 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-06-18 01:46 |
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Publish the Manuscript Online |
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2026-06-25 06:40 |
| ISSN |
1949-8470 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Radiology, Nuclear Medicine & Medical Imaging |
| Manuscript Type |
Correspondence |
| Article Title |
Letter to the Editor: Beyond the liver - integrating emerging predictors in hepatic encephalopathy after transjugular intrahepatic portosystemic shunt
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Cristian Lindner, Andrés Concha and David Clemo |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Cristian Lindner, MD, Department of Radiology, Faculty of Medicine, University of Concepción, San Martín 1436, Concepción 4030000, Chile. clindner146@gmail.com |
| Key Words |
Hepatic encephalopathy; Transjugular intrahepatic portosystemic shunt; Cerebral blood flow; Sarcopenia; Portal hypertension |
| Core Tip |
While Zhuang et al identify cerebral hypoperfusion as a hallmark of post-transjugular intrahepatic portosystemic shunt encephalopathy, this letter argues that these changes represent the final downstream consequence of a systemic multi-hit failure. We integrate emerging evidence on the gut-liver-muscle axis, emphasizing that sarcopenia, the AMMON-OHE model, and shunt magnitude are critical upstream determinants of neurotoxicity. We propose that to prevent cognitive decline, specialists must move beyond isolated hemodynamic targets and adopt a precision medicine approach, tailoring stent expansion to the patient's individual metabolic and muscular reserve. |
| Publish Date |
2026-06-25 06:40 |
| Citation |
Lindner C, Concha A, Clemo D. Letter to the Editor: Beyond the liver - integrating emerging predictors in hepatic encephalopathy after transjugular intrahepatic portosystemic shunt. World J Radiol 2026; 18(6): 119600
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| URL |
https://www.wjgnet.com/1949-8470/full/v18/i6/119600.htm |
| DOI |
https://doi.org/10.4329/wjr.119600 |
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