BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
6/25/2026 6:40:07 AM | Browse: 0 | Download: 0
Publication Name World Journal of Radiology
Manuscript ID 119600
Country Chile
Received
2026-02-02 00:51
Peer-Review Started
2026-02-02 00:52
First Decision by Editorial Office Director
2026-02-12 08:25
Return for Revision
2026-02-12 08:25
Revised
2026-02-20 00:33
Publication Fee Transferred
Second Decision by Editor
2026-03-24 02:48
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-03-24 07:50
Articles in Press
2026-03-24 07:50
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-06-18 01:46
Publish the Manuscript Online
2026-06-25 06:40
ISSN 1949-8470 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type Correspondence
Article Title Letter to the Editor: Beyond the liver - integrating emerging predictors in hepatic encephalopathy after transjugular intrahepatic portosystemic shunt
Manuscript Source Invited Manuscript
All Author List Cristian Lindner, Andrés Concha and David Clemo
ORCID
Author(s) ORCID Number
Cristian Lindner http://orcid.org/0000-0002-2642-4288
Funding Agency and Grant Number
Corresponding Author Cristian Lindner, MD, Department of Radiology, Faculty of Medicine, University of Concepción, San Martín 1436, Concepción 4030000, Chile. clindner146@gmail.com
Key Words Hepatic encephalopathy; Transjugular intrahepatic portosystemic shunt; Cerebral blood flow; Sarcopenia; Portal hypertension
Core Tip While Zhuang et al identify cerebral hypoperfusion as a hallmark of post-transjugular intrahepatic portosystemic shunt encephalopathy, this letter argues that these changes represent the final downstream consequence of a systemic multi-hit failure. We integrate emerging evidence on the gut-liver-muscle axis, emphasizing that sarcopenia, the AMMON-OHE model, and shunt magnitude are critical upstream determinants of neurotoxicity. We propose that to prevent cognitive decline, specialists must move beyond isolated hemodynamic targets and adopt a precision medicine approach, tailoring stent expansion to the patient's individual metabolic and muscular reserve.
Publish Date 2026-06-25 06:40
Citation

Lindner C, Concha A, Clemo D. Letter to the Editor: Beyond the liver - integrating emerging predictors in hepatic encephalopathy after transjugular intrahepatic portosystemic shunt. World J Radiol 2026; 18(6): 119600

URL https://www.wjgnet.com/1949-8470/full/v18/i6/119600.htm
DOI https://doi.org/10.4329/wjr.119600
Full Article (PDF) WJR-18-119600-with-cover.pdf
Manuscript File 119600_Auto_Edited_060249.docx
Answering Reviewers 119600-answering-reviewers.pdf
Audio Core Tip 119600-audio.ogg
Conflict-of-Interest Disclosure Form 119600-conflict-of-interest-statement.pdf
Copyright License Agreement 119600-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 119600-non-native-speakers.pdf
Peer-review Report 119600-peer-reviews.pdf
Scientific Misconduct Check 119600-scientific-misconduct-check.png
Scientific Editor Work List 119600-scientific-editor-work-list.pdf
CrossCheck Report 119600-crosscheck-report.pdf