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Articles Published Processes
9/9/2026 9:45:09 AM | Browse: 2 | Download: 0
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Received |
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2026-03-25 10:20 |
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Peer-Review Started |
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2026-03-25 10:20 |
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First Decision by Editorial Office Director |
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2026-04-15 07:45 |
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Return for Revision |
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2026-04-15 07:45 |
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Revised |
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2026-06-02 10:24 |
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Publication Fee Transferred |
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2026-06-08 06:05 |
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Second Decision by Editor |
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2026-06-23 02:18 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-06-23 03:45 |
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Articles in Press |
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2026-06-23 03:45 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-08-18 01:08 |
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Publish the Manuscript Online |
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2026-09-09 09:45 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Triplet vs doublet adjuvant chemotherapy for gastric cancer: A systematic review and meta-analysis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Chang-Tao Yu, Jin-Kai Wang, Bai-Xue Qin and Guang-Yuan Wang |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Guang-Yuan Wang, Department of Gastroenterology, The Second People’s Hospital of Liaocheng, No. 306, Jiankang Street, Xianfeng Subdistrict Office, Linqing City, Liaocheng 252600, Shandong Province, China. guangyuanwang2025@163.com |
| Key Words |
Gastric cancer; Adjuvant chemotherapy; Postoperative chemotherapy; Triplet chemotherapy; Doublet chemotherapy; Meta-analysis |
| Core Tip |
This comprehensive meta-analysis of 12 randomized controlled trials encompassing 11126 patients demonstrates that taxane-platinum-fluoropyrimidine triplet chemotherapy significantly improves objective response rate (1.73-fold increase) and disease control rate (1.22-fold increase) compared to platinum-fluoropyrimidine doublet regimens in neoadjuvant treatment of gastric cancer. Despite superior tumor response, no significant survival benefits were observed. Importantly, safety profiles were comparable between regimens. These findings support individualized treatment selection, with triplet regimens preferred for maximal tumor downstaging when surgical resectability is borderline. |
| Publish Date |
2026-09-09 09:45 |
| Citation |
Yu CT, Wang JK, Qin BX, Wang GY. Triplet vs doublet adjuvant chemotherapy for gastric cancer: A systematic review and meta-analysis. World J Gastrointest Oncol 2026; 18(9): 119632
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| URL |
https://www.wjgnet.com/1948-5204/full/v18/i9/119632.htm |
| DOI |
https://doi.org/10.4251/wjgo.119632 |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
